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1.47574

Phosphate de sodium dibasic heptahydraté

granulated, DAC, USP, EMPROVE® EXPERT

Synonyme(s) :

Hydrogénophosphate de disodium heptahydraté, Phosphate disodique

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A propos de cet article

Formule linéaire :
Na2HPO4 · 7H2O
Numéro CAS:
7782-85-6
Poids moléculaire :
268.07
UNSPSC Code:
12352200
MDL number:
MFCD00149180
Form:
granular
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Quality Level

500

agency

DAC, USP

vapor density

4.9 (vs air)

product line

EMPROVE® EXPERT

form

granular

impurities

low in endotoxins

density

1.68 g/mL at 25 °C (lit.)

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharma/biopharma processes
pharma/biopharma processes

storage temp.

15-25°C

SMILES string

O.O.O.O.O.O.O.[Na+].[Na+].OP([O-])([O-])=O

InChI

1S/2Na.H3O4P.7H2O/c;;1-5(2,3)4;;;;;;;/h;;(H3,1,2,3,4);7*1H2/q2*+1;;;;;;;;/p-2

InChI key

PYLIXCKOHOHGKQ-UHFFFAOYSA-L

General description

Standard bulk materials often show a tendency for caking, clumping and dust formation which results in laborious weighing and manual de-caking processes with a negative impact on manufacturing efficiency. Due to its granulated form, di-Sodium hydrogen phosphate heptahydrate granulated is free-flowing and easy to handle. Its greatly reduced caking behavior facilitates processability, speeds up manufacturing processes and increases operator safety. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

di-Sodium hydrogen phosphate heptahydrate is used as a buffer component for Biomolecule downstream processing steps and final formulation as well as small molecule final formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Classe de stockage

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificats d'analyse (COA)

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Articles

Facilitate Handling of Bulk Powders with Dry Granulation

Handling bulk powders at a large scale in the pharmaceutical, biopharmaceutical, and bioprocessing setting is challenging. Compared to powders, granulated materials experience far less caking, have better flowability, and are easier to handle, even after long-term storage.