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1.02839

L-cystéine hydrochloride monohydrate

Name: <SC>L</SC>-cystéine hydrochloride monohydrate
Brand: MM

for biochemistry

Synonyme(s) :

Cys, L-Cysteinium Chloride Monohydrate, L-Cysteine Hydrochloride, Monohydrate

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A propos de cet article

Formule linéaire :

HSCH₂CH(NH₂)COOH · HCl · H₂O

Numéro CAS:

7048-04-6

Poids moléculaire :

175.63

UNSPSC Code:

12352209

NACRES:

NA.21

EC Index Number:

200-157-7

MDL number:

MFCD00065606

Beilstein/REAXYS Number:

5158059

Assay:

98.5-101.0% dry basis (alkalimetric)

Form:

crystalline powder

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Propriétés

vapor pressure

<0.1 hPa ( 20 °C)

Quality Level

100

assay

98.5-101.0% dry basis (alkalimetric)

form

crystalline powder

pH

0.8-1.2 (20 °C, 100 g/L in H₂O)

mp

168-170 °C

solubility

650 g/L

density

1.54 g/cm³

bulk density

780 kg/m³

anion traces

sulfate (SO₄^2-): ≤300 ppm

cation traces

Fe: ≤20 ppm, heavy metals (as Pb): ≤10 ppm

storage temp.

2-30°C

SMILES string

O.Cl.N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1

InChI key

QIJRTFXNRTXDIP-JIZZDEOASA-N

Description

Application

Smartphone-based Ellman′s colourimetric methods for the analysis of d-penicillamine formulation and thiolated polymer: Demonstrates the application of L-Cysteine hydrochloride monohydrate in developing colorimetric assays for pharmaceutical analysis, enhancing the accessibility and cost-effectiveness of drug quality control (Phadungcharoen et al., 2019).

The effects of the thiolation with thioglycolic acid and l-cysteine on the mucoadhesion properties of the starch-graft-poly(acrylic acid): Focuses on the modification of polymers with L-Cysteine hydrochloride monohydrate to improve their mucoadhesive properties, which is critical for developing more effective drug delivery systems (Gök et al., 2017).

On-line pre-reduction of pentavalent arsenicals by thioglycolic acid for speciation analysis by selective hydride generation-cryotrapping-atomic absorption spectrometry: Utilizes L-Cysteine hydrochloride monohydrate in analytical chemistry techniques to improve the detection and measurement of toxic elements in environmental samples, crucial for monitoring and ensuring public health (Musil et al., 2008).

Biochem/physiol Actions

Il s′agit d′un antagoniste des récepteurs glutamatergiques de type NMDA.

Analysis Note

Assay (alkalimetric, calculated on dried substance): 98.5 - 101.0 %
Identity (IR-spectrum): passes test
Identity (Chloride): passes test
Appearance: white or almost white, crystalline powder or colorless crystals
Appearance of solution (25 g/l, water): clear and not more intense in color than reference solution BY6
Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance): +5.5 to +7.0
Spec. rotation (α 25/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance): +5.7 to +6.8
Sulfate (SO₄): ≤ 300 ppm
Heavy metals (as Pb): ≤ 10 ppm
Fe (Iron): ≤ 20 ppm
Related Compounds, total (TLC): ≤ 0.5 %
Ninhydrin-positive substances (LC)(impurity A (570 nm)): ≤ 0.5 %
Ninhydrin-positive substances (LC)(any ninhydrin-positive impurity): ≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm)): ≤ 0.02 %
Ninhydrin-positive substances (LC)(total impurities): ≤ 1.0 %
Residual solvents (ICH Q3C): excluded by manufacturing process
Sulfated ash (600 °C): ≤ 0.1 %
Loss on drying (Vacuum < 0.7 kPa, P₂O₅, 24 h): 8.0 - 12.0 %
Bacterial endotoxins: ≤ 6.0 I.U./g

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Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c