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880129C

Avanti

DSPE-PEG(2000) Biotin

Avanti Research - A Croda Brand

Synonyme(s) :

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotinyl(polyethylene glycol)-2000] (ammonium salt)

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A propos de cet article

Numéro CAS:
UNSPSC Code:
12352211
NACRES:
NA.25
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Nom du produit

DSPE-PEG(2000) Biotin, Avanti Research - A Croda Brand 880129C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (880129C-10mg), pkg of 1 × 2 mL (880129C-50mg), pkg of 1 × 2.5 mL (880129C-25mg), pkg of 1 × 4 mL (880129C-100mg)

manufacturer/tradename

Avanti Research - A Croda Brand 880129C

concentration

10 mg/mL (880129C-10mg), 10 mg/mL (880129C-25mg), 25 mg/mL (880129C-100mg), 25 mg/mL (880129C-50mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO/C=C\NC(CCCC[C@](SC[C@@]1(NC(N2)=O)[H])([C@]12[H])[H])=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=

General description

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotinyl(polyethylene glycol)-2000] (DSPE-PEG(2000) based micelles display a spheroids shape and are effective agents for drug delivery. Their size ranges between 18 nm to 90 nm. It is used with functional groups like biotin added as conjugate.

Application

DSPE-PEG(2000) Biotin has been used in the generation of biotinylated lipid-coated microbubbles for adhering to human umbilical vein endothelial cells (HUVECs) and chicken embryo for ultrasound studies. It has also been used for the generation of giant unilamellar lipid vesicles (GUVs) for live cell fusion studies.

Biochem/physiol Actions

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotinyl(polyethylene glycol)-2000] (DSPE-PEG(2000)) Biotin is used in capsule surface modification.

Packaging

5 mL Clear Glass Sealed Ampule (880129C-100mg)
5 mL Clear Glass Sealed Ampule (880129C-10mg)
5 mL Clear Glass Sealed Ampule (880129C-25mg)
5 mL Clear Glass Sealed Ampule (880129C-50mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

Classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash



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In vivo characterization of ultrasound contrast agents: microbubble spectroscopy in a chicken embryo
Faez T, et al.
Ultrasound in Medicine & Biology, 38(9), 1608-1617 (2012)
SPIO labeling of endothelial cells using ultrasound and targeted microbubbles at diagnostic pressures
Skachkov I, et al.
Testing, 13(9), e0204354-e0204354 (2018)
Hot-nanoparticle-mediated fusion of selected cells
Bahadori A, et al.
Nano Research, 10(6), 2034-2045 (2017)



Numéro d'article de commerce international

RéférenceGTIN
880129C-10MG04061837668340
880129C-100MG04061837668333
880129C-25MG04061837668357
880129C-50MG04061837668364