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A propos de cet article
Formule empirique (notation de Hill) :
C40H80NO8P
Numéro CAS:
Poids moléculaire :
734.04
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
Service technique
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14:0-18:0 PC, 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 200 mg (850446P-200mg), pkg of 1 × 25 mg (850446P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850446P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O
InChI
1S/C40H80NO8P/c1-6-8-10-12-14-16-18-19-20-21-23-25-27-29-31-33-40(43)49-38(37-48-50(44,45)47-35-34-41(3,4)5)36-46-39(42)32-30-28-26-24-22-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1
InChI key
TYAQXZHDAGZOEO-KXQOOQHDSA-N
General description
Phosphatidylcholine (PC) is one of the most important constituent of colon′s mucosal layer. 14:0-18:0 PC (1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine) is an asymmetrical lipid with long alkyl side chain.
Application
14:0-18:0 PC (1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine) may be used:
- in lipid bilayers to study its miscibility with d-erythro-N-palmitoyl-sphingomyelin (16:0-SM) using differential scanning calorimetry (DSC)
- as an asymmetrical lipid component in liposomes to study the impact of bilayer area and lipid geometry and as liposomal solubilizing agents
- to prepare a low temperature-sensitive liposome for thrombolytic studies
Biochem/physiol Actions
Phosphatidylcholine (PC) forms a hydrophobic surface in the mucus by acting as a surfactant resulting in the inhibition of penetrance of bacteria.
Packaging
5 mL Amber Glass Screw Cap Vial (850446P-200mg)
5 mL Amber Glass Screw Cap Vial (850446P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Classe de stockage
11 - Combustible Solids
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In this study we have used differential scanning calorimetry (DSC) to study the miscibility of different saturated phosphatidylcholines (PCs) with D-erythro-N-palmitoyl-sphingomyelin (16:0-SM). Information about the miscibility was obtained by observing the thermotropic phase behavior of binary mixtures of saturated PCs
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| 850446P-200MG | 04061835230808 |
| 850446P-25MG | 04061835230815 |