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850346C

Avanti

14:1 (Δ9-Cis) PC

Avanti Research - A Croda Brand

Synonyme(s) :

1,2-di-(9Z-tetradecenoyl)-sn-glycero-3-phosphocholine; PC(14:1(9Z)/14:1(9Z))

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A propos de cet article

Formule empirique (notation de Hill) :
C36H68NO8P
Numéro CAS:
Poids moléculaire :
673.90
MDL number:
NACRES:
NA.25
UNSPSC Code:
51191904
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Nom du produit

14:1 (Δ9-Cis) PC, 1,2-dimyristoleoyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850346C-25mg), pkg of 2 × 4 mL (850346C-200mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850346C

concentration

10 mg/mL (850346C-25mg), 25 mg/mL (850346C-200mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

General description

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Phosphatidylcholine (PC) belongs to the class of glycerophospholipid. It is the prime cellular phospholipid.
Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.

Application

14:1 (Δ9-Cis) PC has been used in the liposome preparation. It has also been used as an internal standard for the extraction of lipids from the interstitial fractions of lung tissues for electrospray ionisation-mass spectrometry (ESI-MS) analysis.

Biochem/physiol Actions

Phosphatidylcholine (PC) contributes to the membrane structure. Each cell type and tissue maintain a unique PC profile. PC plays a key role in cell signaling. Disruption in the homeostasis of PC leads to cell death in mammalian cells. PC is present in bile and aids in lipid emulsification in the diet. It is known to reduce cholesterol and triglyceride levels. It is administered for treating fat embolism and cardiac ischemia. Monounsaturated PC 14:1 (Δ9-Cis) is known to inhibit cell proliferation in different cell lines.
Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

Packaging

5 mL Clear Glass Sealed Ampule (850346C-200mg)
5 mL Clear Glass Sealed Ampule (850346C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

Classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash



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Consulter la Bibliothèque de documents



Phosphatidylcholine and cell death
Cui Z and Houweling M
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1585(2-3), 87-96 (2002)
Integrative Medicine - E-Book (2017)
Bilayer thickness and curvature influence binding and insertion of a pHLIP peptide
Karabadzhak AG, et al.
Biophysical Journal, 114(9), 2107-2115 (2018)



Numéro d'article de commerce international

RéférenceGTIN
850346C-200MG04061837792045
850346C-25MG04061837792052