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846725C

Avanti

18:1 Lyso PE

Avanti Research™ - A Croda Brand

Synonyme(s) :

1--(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; PE(18:1(9Z)/0:0)

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A propos de cet article

Formule empirique (notation de Hill) :
C23H46NO7P
Numéro CAS:
89576-29-4
Poids moléculaire :
479.59
UNSPSC Code:
51191904
NACRES:
NA.25
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Nom du produit

18:1 Lyso PE, 1-oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine, chloroform

assay

>99% (LPE; may contain up to 10% of the 2-LPE isomer, TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (846725C-25mg), pkg of 2 × 20 mL (846725C-1g), pkg of 2 × 4 mL (846725C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 846725C

concentration

10 mg/mL (846725C-25mg), 25 mg/mL (846725C-1g), 25 mg/mL (846725C-200mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[NH3+])=O)([H])COC(CCCCCCC/C=C\CCCCCCCC)=O

InChI key

PYVRVRFVLRNJLY-MZMPXXGTSA-N

General description

Lyso-phosphatidylethanolamine (lysoPE) is a structural isomer which carries an oleic acid at the sn-1 position. This lipid occurs naturally.

Application

18:1 Lyso PE (1-oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine) has been used as a lipid standard in the optimization of the liquid chromatography−mass spectrometry (LC-MS) method conditions. It may be used to study its effects on [Ca2+]i in PC-12 neuronal cells, MDA-MB-231 and SK-OV3 cells.

Biochem/physiol Actions

Lyso-phosphatidylethanolamine (lysoPE) can serve as a substrate for SocA, the short-chain alcohol dehydrogenase. It helps to delay the senescence in the plant parts.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (846725C-1g)
5 mL Clear Glass Sealed Ampule (846725C-200mg)
5 mL Clear Glass Sealed Ampule (846725C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

Classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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Soo-Jin Park et al.
Biomolecules & therapeutics, 22(2), 129-135 (2014-04-23)
Previously, we reported that lysophosphatidylethanolamine (LPE), a lyso-type metabolite of phosphatidylethanolamine, can increase intracellular Ca(2+) ([Ca(2+)]i) via type 1 lysophosphatidic acid (LPA) receptor (LPA1) and CD97, an adhesion G-protein-coupled receptor (GPCR), in MDA-MB-231 breast cancer cells. Furthermore, LPE signaling was
Kelly M Hines et al.
Chemistry and physics of lipids, 219, 15-22 (2019-01-21)
Our understanding of phospholipid biosynthesis in Gram-positive and Gram-negative bacteria is derived from the prototypical Gram-negative organism Escherichia coli. The inner and outer membranes of E. coli are largely composed of phosphatidylethanolamine (PE), minor amounts of phosphatidylglycerol (PG) and cardiolipin
Madhavi Avadhani et al.
Journal of bacteriology, 188(24), 8543-8550 (2006-10-10)
Short-chain alcohol dehydrogenases (SCADHs) synthesize a variety of intercellular signals and other chemically diverse products. It is difficult to predict the substrate of a SCADH on the basis of amino acid sequence homology, as the substrates are not known for
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Numéro d'article de commerce international

RéférenceGTIN
846725C-1G04061837791789
846725C-200MG04061837791796
846725C-25MG04061837791802