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W381918

L-Arginine

Name: <SC>L</SC>-Arginine
Brand: ALDRICH

99%, FCC, FG

Synonyme(s) :

Acide (S)-2-amino-5-guanidinopentanoïque

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A propos de cet article

Formule linéaire :

H₂NC(=NH)NH(CH₂)₃CH(NH₂)CO₂H

Numéro CAS:

74-79-3

Poids moléculaire :

174.20

FEMA Number:

3819

UNSPSC Code:

12164502

eCl@ss:

32160406

PubChem Substance ID:

24901894

NACRES:

NA.21

EC Number:

200-811-1

Flavis number:

17.003

MDL number:

MFCD00002635

Beilstein/REAXYS Number:

1725413

Organoleptic:

faint

Grade:

Biological source:

synthetic

Agency:

meets purity specifications of JECFA

Food allergen:

no known allergens

Service technique

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Propriétés

biological source

synthetic

Quality Level

300

grade

agency

meets purity specifications of JECFA

reg. compliance

EU Regulation 1334/2008 & 872/2012, FCC, FDA 21 CFR 172.320

assay

99%

form

powder or crystals

optical activity

[α]20/D +27°, c = 8 in 6 M HCl

mp

222 °C (dec.) (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

faint

SMILES string

N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1

InChI key

ODKSFYDXXFIFQN-BYPYZUCNSA-N

Gene Information

human ... NOS1(4842), NOS2(4843)
rat ... Ppm1a(24666)

Description

General description

L-Arginine is an amino acid that plays a key role in many physiological processes such as tissue repair and reproduction. It is a key precursor for synthesizing nitric oxide in mammals. Due to these factors, the dietary supplementation with L-arginine may show a range of health benefits.

Application

Metabolomic approaches to dissect dysregulated metabolism in the progression of pre-diabetes to T2DM.: This study employs L-Arginine to examine metabolic changes during the transition from pre-diabetes to type 2 diabetes mellitus, offering new targets for early intervention (Ji et al., 2024 Jun). Link to the article.

Amino acid profile alteration in age-related atrial fibrillation.: Investigates the role of L-Arginine in cardiovascular aging, highlighting its potential in developing therapeutic strategies against atrial fibrillation associated with aging (Huang et al., 2024 Mar). Link to the article.

Biochem/physiol Actions

Substrat de l′oxyde nitrique synthase qui est converti en citrulline et oxyde nitrique (NO). Induit la libération d′insuline par un mécanisme dépendant de l′oxyde nitrique.

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Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number

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Blood pressure and metabolic changes during dietary L-arginine supplementation in humans.

Siani A, et al.

American Journal of Hypertension, 13(5), 547-551 (2000)

L-Arginine Research Progress (2012)

Automethylation of protein arginine methyltransferase 6 (PRMT6) regulates its stability and its anti-HIV-1 activity.

Diane N Singhroy et al.

Retrovirology, 10, 73-73 (2013-07-23)

Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that methylates arginine residues on histones and transcription factors. In addition, PRMT6 inhibits HIV-1 replication in cell culture by directly methylating and interfering with the functions of several HIV-1 proteins, i.e.

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Numéro d'article de commerce international

Référence	GTIN
W381918-10KG	04061838258106
W381918-1KG	04061838258113
W381918-5KG	04061838258120
W381918-SAMPLE	04061837537509