925144
KB05yne
≥95%
Synonyme(s) :
4-(N-(4-Bromophenyl)acrylamido)-N-(hex-5-yn-1-yl)benzamide, Functionalized scout fragment
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A propos de cet article
Formule empirique (notation de Hill) :
C22H21BrN2O2
Poids moléculaire :
425.32
NACRES:
NA.22
UNSPSC Code:
12352101
Service technique
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Laissez-nous vous aiderQuality Level
assay
≥95%
form
powder or solid
reaction suitability
reagent type: chemical modification reagent
reaction type: click chemistry
storage temp.
2-8°C
Application
KB05yne is a cysteine-reactive small-molecule fragment for chemoproteomic and ligandability studies for both traditionally druggable proteins as well as "undruggable," or difficult-to-target, proteins. This fragment electrophile is the functionalized version of KB02 (912131)
Related useful products may include: Cysteine-reactive fragments: KB02 (912131), KB03 (912654), KB05 (911798), sulfoxide (925136), CoLDR probe (923818) Functionalized scout fragments: KB02-COOH (925047), KB02yne (925225) Electrophilic degraders featuring scout fragments: KB02-SLF (914738), KB03-SLF (914975), KB05-SLF (913715), Biotin-SLF (914223) Cysteine-reactive probes for chemoproteomics: IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059)Related useful products may include: Cysteine-reactive fragments: KB02 (912131), KB03 (912654), KB05 (911798), sulfoxide (925136), CoLDR probe (923818) Functionalized scout fragments: KB02-COOH (925047), KB02yne (925225) Electrophilic degraders featuring scout fragments: KB02-SLF (914738), KB03-SLF (914975), KB05-SLF (913715), Biotin-SLF (914223) Cysteine-reactive probes for chemoproteomics: IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059)
Technology spotlight: Proteomic Ligandability Assessment
Related useful products may include: Cysteine-reactive fragments: KB02 (912131), KB03 (912654), KB05 (911798), sulfoxide (925136), CoLDR probe (923818) Functionalized scout fragments: KB02-COOH (925047), KB02yne (925225) Electrophilic degraders featuring scout fragments: KB02-SLF (914738), KB03-SLF (914975), KB05-SLF (913715), Biotin-SLF (914223) Cysteine-reactive probes for chemoproteomics: IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059)Related useful products may include: Cysteine-reactive fragments: KB02 (912131), KB03 (912654), KB05 (911798), sulfoxide (925136), CoLDR probe (923818) Functionalized scout fragments: KB02-COOH (925047), KB02yne (925225) Electrophilic degraders featuring scout fragments: KB02-SLF (914738), KB03-SLF (914975), KB05-SLF (913715), Biotin-SLF (914223) Cysteine-reactive probes for chemoproteomics: IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059)
Technology spotlight: Proteomic Ligandability Assessment
Classe de stockage
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16
Xiaoyu Zhang, et al
Nature Chemical Biology, 15(7), 737-746 (2019)
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| 925144-10MG | 04065267418353 |