150215
9(10H)-Acridanone
99%
Synonyme(s) :
Acridone, 9,10-Dihydro-9-oxoacridine
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A propos de cet article
Formule empirique (notation de Hill) :
C13H9NO
Numéro CAS:
Poids moléculaire :
195.22
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
209-434-7
Beilstein/REAXYS Number:
7104
MDL number:
Assay:
99%
Form:
solid
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assay
99%
form
solid
mp
>300 °C (lit.)
λmax
380 nm, 399 nm (2nd)
SMILES string
O=C1c2ccccc2Nc3ccccc13
InChI
1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15)
InChI key
FZEYVTFCMJSGMP-UHFFFAOYSA-N
Gene Information
human ... ABCB1(5243)
Application
9(10H)-Acridanone (acridone) was used in the preparation of methyl 9,10-dihydro-9-oxoacridine-10-pentanoate.
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Alessandra Di Veroli et al.
Environmental pollution (Barking, Essex : 1987), 166, 212-217 (2012-04-21)
The aim of the present study was to improve the cause-effect relationship between toxicant exposure and chironomid mouthpart deformities, by linking induction of mouthpart deformities to contaminated field sediments, metal mixtures and a mutagenic polycyclic aromatic compound metabolite (acridone). Mouthpart
Vishal P Zambre et al.
Journal of molecular graphics & modelling, 29(2), 229-239 (2010-08-10)
G-quadruplex structures of DNA represent a potentially useful target for anticancer drugs. Telomerase enzyme, involved in immortalization of cancer cells is inhibited by stabilization of G-quadruplex at the ends of chromosomes. Anthraquinone and acridone derivatives are promising G-quadruplex ligands as
O Arnaud et al.
European journal of cancer (Oxford, England : 1990), 47(4), 640-648 (2011-01-11)
The breast cancer resistance protein ABCG2 confers cellular resistance to irinotecan (CPT-11) and its active metabolite SN-38. We utilised ABCG2-expressing xenografts as a model to evaluate the ability of a non-toxic ABCG2 inhibitor to increase intracellular drug accumulation. We assessed
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| 342432-500G | 04061826757338 |
| 342432-100G | 04061826757314 |
| 150215-5G | 04061831818727 |
| 150215-1G | 04061825583037 |