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RRM1

ribonucleotide reductase M1

Synonymes:
R1, RIR1, RR1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6240) Summary: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008]
  • Mouse(20133) ribonucleotide reductase M1
  • Rat(685579) ribonucleotide reductase M1
  • Zebrafish(30740) ribonucleotide reductase M1 polypeptide
  • chicken(419081) ribonucleotide reductase M1
  • domestic cat(101097343) ribonucleotide reductase M1
  • Horse(100053126) ribonucleotide reductase M1
  • dog(476823) ribonucleotide reductase M1
  • Domestic Rabbit(100345823) ribonucleotide reductase M1
  • naked mole-rat(101708047) ribonucleotide reductase M1
  • domestic guinea pig(100728488) ribonucleotide reductase M1
  • cow(505537) ribonucleotide reductase M1
  • sheep(101116171) ribonucleotide reductase M1

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-RRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-RRM1 Antibody, clone 1E20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey
Application
affinity binding assay
flow cytometry

immunohistochemistry

western blot
Anti-RRM1 Antibody, clone 4P4U1, Rabbit Monoclonal, ,
Espèces réactives
human, rat
Application
western blot
Anti-RRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
Hydroxyurée, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Hydroxyurée, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Hydroxyurée, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human
Hydroxyurée, 98%, powder,
Espèce(s)
human
Gemcitabine hydrochloride, ≥98% (HPLC),
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human RRM1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Rrm1,
Espèce(s)
mouse