REN
renin
Synonyms:
HNFJ2
Species:
Human REN (5972), Rat Ren (24715), cow REN (280909), sheep REN (443310), naked mole-rat Ren (101725618), domestic guinea pig Ren (100724037), fruit fly ren (44122), domestic cat REN (101081695), dog REN (403838), Zebrafish ren (405786)
UniProtKB ID:
Gene ID:
- Human(5972) Summary: Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]
- Rat(24715) renin
- cow(280909) renin
- sheep(443310) renin
- naked mole-rat(101725618) renin
- domestic guinea pig(100724037) renin
- fruit fly(44122) renegade
- domestic cat(101081695) renin
- dog(403838) renin
- Zebrafish(405786) renin
- chicken(431167) renin
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Custom Gene Products
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-REN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-REN antibody produced in mouse, clone 2H2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-REN antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-REN antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, human, mouse, rat, sheep
Application
western blot
Monoclonal Anti-REN, (C-terminal) antibody produced in mouse, clone 3B5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Small Molecule - Inhibitor
Kits
Product Number
Description
Species
esiRNA
Product Number
Description
Species