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PRKCQ

protein kinase C, theta

Synonyms:
PRKCT, nPKC-theta
Species:
UniProtKB ID:
Gene ID:
  • Human(5588) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008]
  • Mouse(18761) protein kinase C, theta
  • Rat(85420) protein kinase C, theta
  • naked mole-rat(101724103) protein kinase C, theta
  • domestic guinea pig(100726308) protein kinase C, theta
  • cow(505901) protein kinase C, theta
  • sheep(101113426) protein kinase C, theta
  • Zebrafish(555521) protein kinase C, theta
  • domestic cat(101100730) protein kinase C, theta
  • Horse(100070207) protein kinase C, theta
  • dog(478013) protein kinase C, theta
  • chicken(776459) protein kinase C, theta

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Phospho-PRKCQ-T538 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
Anti-PRKCQ antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-phospho-PRKCQ (pSer695) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-phospho-PKC θ (pThr538) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti PKC theta Antibody, clone 23GB4105, Rabbit Monoclonal, clone 23GB4105, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
flow cytometry
immunofluorescence

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
UCN-01, ≥97% (HPLC), powder,
Species
human
GSK690693, ≥98% (HPLC),
Species
human

Proteins

Product Number
Description
Species
N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala, ,
Species
mouse
PKC θ Protein, active, 10 µg, Active, recombinant full-length human PKC theta with a C-terminal 6His-tag. For use in Kinase Assays.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Prkcq,
Species
mouse
MISSION® esiRNA, targeting human PRKCQ,
Species
human