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Merck

PGGT1B

protein geranylgeranyltransferase type I, beta subunit

Synonyms:
BGGI, GGTI
Species:
Human PGGT1B (5229), Mouse Pggt1b (225467), Rat Pggt1b (81746), Zebrafish pggt1b (570808), chicken PGGT1B (770633), domestic cat PGGT1B (101089829), dog PGGT1B (481440), cow PGGT1B (509322), sheep PGGT1B (101123045), domestic guinea pig Pggt1b (100735292)
UniProtKB ID:
P53609, Q5MJP9
Gene ID:
  • Human(5229) Summary: Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]
  • Mouse(225467) protein geranylgeranyltransferase type I, beta subunit
  • Rat(81746) protein geranylgeranyltransferase type I, beta subunit
  • Zebrafish(570808) protein geranylgeranyltransferase type I, beta subunit
  • chicken(770633) protein geranylgeranyltransferase type I, beta subunit
  • domestic cat(101089829) protein geranylgeranyltransferase type I, beta subunit
  • dog(481440) protein geranylgeranyltransferase type I, beta subunit
  • cow(509322) protein geranylgeranyltransferase type I, beta subunit
  • sheep(101123045) protein geranylgeranyltransferase type I, beta subunit
  • domestic guinea pig(100735292) protein geranylgeranyltransferase type I, beta subunit
  • naked mole-rat(101723510) protein geranylgeranyltransferase type I, beta subunit

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Antibodies

Product Number
Description
Species Reactivity
Application
WH0005229M2
Monoclonal Anti-PGGT1B antibody produced in mouse, clone 5E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
G5169
GGTI 298 trifluoroacetate salt hydrate, ≥90% (HPLC), film,
Species
human
G5294
GGTI-2133, ≥98% (HPLC), solid,
Species
human
259926
Itaconic anhydride, 95%,
Species
human

esiRNA

Product Number
Description
Species
EHNC027361
MISSION® esiRNA, targeting human PGGT1B (1),
Species
human
EHU112171
MISSION® esiRNA, targeting human PGGT1B (2),
Species
human
EMU041131
MISSION® esiRNA, targeting mouse Pggt1b,
Species
mouse