NTRK1
neurotrophic tyrosine kinase, receptor, type 1
Synonyms:
MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA
Species:
Human NTRK1 (4914), Mouse Ntrk1 (18211), Rat Ntrk1 (59109), Zebrafish ntrk1 (30546), cow NTRK1 (353111), Horse NTRK1 (100064594), domestic cat NTRK1 (101081603), dog NTRK1 (490404), chicken NTRK1 (396337), domestic guinea pig Ntrk1 (100725325) ...More
UniProtKB ID:
Gene ID:
- Human(4914) Summary: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
- Mouse(18211) neurotrophic tyrosine kinase, receptor, type 1
- Rat(59109) neurotrophic tyrosine kinase, receptor, type 1
- Zebrafish(30546) neurotrophic tyrosine kinase, receptor, type 1
- cow(353111) neurotrophic tyrosine kinase, receptor, type 1
- Horse(100064594) neurotrophic tyrosine kinase, receptor, type 1
- domestic cat(101081603) neurotrophic tyrosine kinase, receptor, type 1
- dog(490404) neurotrophic tyrosine kinase, receptor, type 1
- chicken(396337) neurotrophic tyrosine kinase, receptor, type 1
- domestic guinea pig(100725325) neurotrophic tyrosine kinase, receptor, type 1
- naked mole-rat(101724441) neurotrophic tyrosine kinase, receptor, type 1
- Domestic Rabbit(100354292) neurotrophic tyrosine kinase, receptor, type 1
- sheep(101109763) neurotrophic tyrosine kinase, receptor, type 1
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
ANTI-PHOSPHO-TRKA(Y791) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
Anti-phospho-NTRK1 (pSer791) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
Anti-TrkA Antibody, clone 6B2, ascites fluid, clone 6B2, from mouse,
Species Reactivity
human, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TrkA Antibody, clone 9F4Y9, Rabbit Monoclonal, ,
Species Reactivity
mouse, rat
Application
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
TRKA (440-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human