MVK
mevalonate kinase
Synonyms:
LRBP, MK, MVLK, POROK3
Species:
Human MVK (4598), Mouse Mvk (17855), Rat Mvk (81727), Zebrafish mvk (492477), cow MVK (505792), domestic cat MVK (101085666), dog MVK (486309), chicken MVK (768555), naked mole-rat Mvk (101707794), Domestic Rabbit MVK (100340365) ...More
UniProtKB ID:
Gene ID:
- Human(4598) Summary: This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(17855) mevalonate kinase
- Rat(81727) mevalonate kinase
- Zebrafish(492477) mevalonate kinase
- cow(505792) mevalonate kinase
- domestic cat(101085666) mevalonate kinase
- dog(486309) mevalonate kinase
- chicken(768555) mevalonate kinase
- naked mole-rat(101707794) mevalonate kinase
- Domestic Rabbit(100340365) mevalonate kinase
- domestic guinea pig(100714338) mevalonate kinase
- sheep(101113796) mevalonate kinase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MVK antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, mouse, pig, rabbit, rat
Application
western blot
Anti-MVK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-MVK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-MVK, (C-terminal) antibody produced in mouse, clone 2C5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot