CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
Synonyms:
CP1B, CYPIB1, GLC3A, P4501B1
Species:
Human CYP1B1 (1545), Mouse Cyp1b1 (13078), Rat Cyp1b1 (25426), Zebrafish cyp1b1 (100150054), cow CYP1B1 (511470), dog CYP1B1 (483038), chicken CYP1B1 (428832), chicken CYP1B1 (421466)
UniProtKB ID:
Gene ID:
- Human(1545) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008]
- Mouse(13078) cytochrome P450, family 1, subfamily b, polypeptide 1
- Rat(25426) cytochrome P450, family 1, subfamily b, polypeptide 1
- Zebrafish(100150054) cytochrome P450, family 1, subfamily B, polypeptide 1
- cow(511470) cytochrome P450, family 1, subfamily B, polypeptide 1
- dog(483038) cytochrome P450, family 1, subfamily B, polypeptide 1
- chicken(428832) cytochrome P450, family 1, subfamily B, polypeptide 1
- chicken(421466) cytochrome P450, family 1, subfamily B, polypeptide 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CYP1B1, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, human, mouse, rabbit, rat
Application
western blot
Anti-Cytochrome P450 1B1 Antibody, serum, Chemicon®,
Species Reactivity
human
Application
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
Cytochrome P450 human, 1B1 Isozyme Microsomes, with P450 Reductase, recombinant, expressed in baculovirus infected insect cells (BTI-TN-5B1-4),
Species
human
esiRNA
Product Number
Description
Species