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Merck

ADAM17

ADAM metallopeptidase domain 17

Synonyms:
ADAM18, CD156B, CSVP, NISBD, TACE
Species:
UniProtKB ID:
Gene ID:
  • Human(6868) Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008]
  • Mouse(11491) a disintegrin and metallopeptidase domain 17
  • Rat(57027) ADAM metallopeptidase domain 17
  • naked mole-rat(101720924) ADAM metallopeptidase domain 17
  • domestic guinea pig(100732916) ADAM metallopeptidase domain 17
  • sheep(101116815) ADAM metallopeptidase domain 17
  • chicken(421931) ADAM metallopeptidase domain 17
  • cow(517541) ADAM metallopeptidase domain 17
  • Horse(100072496) ADAM metallopeptidase domain 17
  • domestic cat(101089004) ADAM metallopeptidase domain 17
  • dog(475662) ADAM metallopeptidase domain 17

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Human TACE ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADAM17/TACE antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-ADAM17 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-ADAM 17, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
Anti-ADAM17 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-ADAM 17 (Cleaved-Arg215) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Adam17,
Species
mouse
MISSION® esiRNA, targeting human ADAM17,
Species
human