SAE0073
Saponin
Synonym(s):
Surfactant Saponin
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About This Item
UNSPSC Code:
12161902
EC Number:
232-462-6
NACRES:
NA.21
description
non-ionic
Quality Level
composition
Sapogenin content, 20-35%
technique(s)
HPLC: suitable, LC/MS: suitable, protein quantification: suitable
sulfated ash
≤10%
Application
Saponins has been used to permeabilize dendritic cells (DCs) for intracellular staining with antibodies.
Biochem/physiol Actions
Saponins are associated with many biological and pharmacological activities. It is known to stimulate immune response in mammals. Saponins possesses antiviral, antifungal, antitumor, anti-inflammatory, hypoglycemic and hypocholesterolemic effects. It is a potent hemolytic, when injected intravaneously. It is also useful as a surfactant to enhance penetration of proteins and other macromolecules through cell membranes. Saponins have also been used as adjuvants for vaccines.
Packaging
10, 25 g in poly bottle
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation
Gotoh K, et al.
Cell Reports, 25(7), 1800-1815 (2018)
Flavia Radogna et al.
Methods in molecular biology (Clifton, N.J.), 2276, 129-141 (2021-06-02)
Cellular energy metabolism is regulated by complex metabolic pathways. Although anaerobic glycolysis was reported as a primary source of energy in cancer leading to a high rate of lactate production, current evidence shows that the main energy source supporting cancer
Sónia A Pinho et al.
The FEBS journal, 289(17), 5198-5217 (2022-02-26)
Cell culture conditions highly influence cell metabolism in vitro. This is relevant for preclinical assays, for which fibroblasts are an interesting cell model, with applications in regenerative medicine, diagnostics and therapeutic development for personalized medicine, and the validation of ingredients for
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAE0073-10G | 04061833343395 |
| SAE0073-25G | 04061833493458 |