S8758
N-Succinyl-Ala-Ala-Phe-7-amido-4-methylcoumarin
protease substrate, ≥98%, powder
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About This Item
Empirical Formula (Hill Notation):
C29H32N4O8
CAS Number:
Molecular Weight:
564.59
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
MDL number:
Product Name
N-Succinyl-Ala-Ala-Phe-7-amido-4-methylcoumarin, protease substrate
Quality Level
assay
≥98%
form
powder
solubility
50% acetic acid: 1 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
CC(NC(=O)CCC(O)=O)C(=O)NC(C)C(=O)NC(Cc1ccccc1)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2
InChI
1S/C29H32N4O8/c1-16-13-26(37)41-23-15-20(9-10-21(16)23)32-29(40)22(14-19-7-5-4-6-8-19)33-28(39)18(3)31-27(38)17(2)30-24(34)11-12-25(35)36/h4-10,13,15,17-18,22H,11-12,14H2,1-3H3,(H,30,34)(H,31,38)(H,32,40)(H,33,39)(H,35,36)
InChI key
HHPVJKZZYOXPLH-UHFFFAOYSA-N
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Naoto Watamura et al.
Molecular psychiatry (2021-11-06)
Alzheimer's disease (AD) is characterized by the deposition of amyloid β peptide (Aβ) in the brain. The neuropeptide somatostatin (SST) regulates Aβ catabolism by enhancing neprilysin (NEP)-catalyzed proteolytic degradation. However, the mechanism by which SST regulates NEP activity remains unclear.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| S8758-25MG | 04061832910215 |
| S8758-5MG | 04061832910222 |