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N3877

Potassium 4-nitrophenyl sulfate

Name: Potassium 4-nitrophenyl sulfate
Brand: SIGMA

sulfatase substrate, chromogenic, ≥98% (TLC), powder

Synonym(s):

4-Nitrophenyl sulfate potassium salt

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About This Item

Linear Formula:

NO₂C₆H₄OSO₂OK

CAS Number:

6217-68-1

Molecular Weight:

257.26

NACRES:

NA.32

PubChem Substance ID:

24897664

UNSPSC Code:

12352204

EC Number:

228-288-5

MDL number:

MFCD00007466

Beilstein/REAXYS Number:

3786392

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Properties

Product Name

Potassium 4-nitrophenyl sulfate, sulfatase substrate

Quality Level

200

assay

≥98% (TLC)

form

powder

mp

246-250 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless to very faintly greenish-yellow (to Very Light Yellow)

shipped in

wet ice

storage temp.

−20°C

SMILES string

[K+].[O-][N+](=O)c1ccc(OS([O-])(=O)=O)cc1

InChI

1S/C6H5NO6S.K/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12;/h1-4H,(H,10,11,12);/q;+1/p-1

InChI key

BITVAZYUWRLLCN-UHFFFAOYSA-M

Description

General description

Chromogenic sulfatase substrate.

Application

Potassium 4-nitrophenyl sulfate has been used:

as a substrate to measure arylsulfatase activity in cell-free coelomic fluid
as a substrate for p-nitrophenyl glycoside-based enzyme assay
to inhibit arylsulfatase
as an inorganic analog of organic aryl ester sulphate

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Maternal and neonatal urinary excretion of sulfate and glucuronide ritodrine conjugates

Brashear WT, et al.

Clinical Pharmacology and Therapeutics, 44(6), 634-641 (1988)

Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity.

Elif Akin Kazancioğlu et al.

Journal of enzyme inhibition and medicinal chemistry, 27(6), 880-885 (2011-12-08)

The possible sulfatase activity of several carbonic anhydrase (CA, EC 4.2.1.1) isoforms have been investigated with a series of synthesized methanesulfonate derivatives of phenols. Four α-CA isozymes, i.e. hCA I, hCA II, hCA IV and hCA VI (h = human

Theoretical comparison of p-nitrophenyl phosphate and sulfate hydrolysis in aqueous solution: implications for enzyme-catalyzed sulfuryl transfer.

Shina Caroline Lynn Kamerlin

The Journal of organic chemistry, 76(22), 9228-9238 (2011-10-11)

Both phosphoryl and sulfuryl transfers are ubiquitous in biology, being involved in a wide range of processes, ranging from cell division to apoptosis. Additionally, it is becoming increasingly clear that enzymes that can catalyze phosphoryl transfer can often cross-catalyze sulfuryl

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Global Trade Item Number

SKU	GTIN
N3877-1G	04061835506477
N3877-5G	04061835506484
N3877-500MG	04061834116325