F7131
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly
chromogenic, ≥99% (HPLC)
Synonym(s):
FAPGG, N-[3-(2-Furyl)acryloyl]-L-phenylalanyl-glycyl-glycine
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About This Item
Empirical Formula (Hill Notation):
C20H21N3O6
CAS Number:
Molecular Weight:
399.40
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.32
MDL number:
Product Name
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly,
Quality Level
storage temp.
−20°C
SMILES string
OC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c2ccco2
InChI
1S/C20H21N3O6/c24-17(9-8-15-7-4-10-29-15)23-16(11-14-5-2-1-3-6-14)20(28)22-12-18(25)21-13-19(26)27/h1-10,16H,11-13H2,(H,21,25)(H,22,28)(H,23,24)(H,26,27)/b9-8+/t16-/m0/s1
InChI key
ZDLZKMDMBBMJLI-FDMDGMSGSA-N
Gene Information
human ... ACE(1636), ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421), ACE2(70008), ACE3(498012)
General description
A substrate for continuous spectrophotometric assay of angiotensin converting enzyme (ACE).
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly acts as a substrate for angiotensin converting enzyme (ACE), and is used in inhibitory assays of ACE.
Application
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly has been used for kinetic spectrophotometric assay of ACE (angiotensin converting enzyme) inhibitory activity.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Md Yousof Ali et al.
Molecules (Basel, Switzerland), 24(21) (2019-11-07)
The bioactivity of ten traditional Korean Angelica species were screened by angiotensin-converting enzyme (ACE) assay in vitro. Among the crude extracts, the methanol extract of Angelica decursiva whole plants exhibited potent inhibitory effects against ACE. In addition, the ACE inhibitory
Zhen-Hao Li et al.
Scientific reports, 7(1), 12243-12243 (2017-09-28)
Quality control is critical for ensuring the safety and effectiveness of drugs. Current quality control method for botanical drugs is mainly based on chemical testing. However, chemical testing alone may not be sufficient as it may not capture all constituents
Anees A Syed et al.
Journal of ethnopharmacology, 193, 555-565 (2016-10-11)
Ulmus wallichiana Planchon (Himalayan Elm), a traditional medicinal plant, used in fracture healing in folk tradition of Uttarakhand, Himalaya, India. It is also used as diuretic. U. rhynchophylla, native to China, known as Gou Teng in Chinese medicine, is used
Global Trade Item Number
| SKU | GTIN |
|---|---|
| F7131-25MG | 04061833619308 |
| F7131-100MG | 04061833619292 |
| F7131-500MG | 04061833619315 |