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Ari E Friedland et al.
Nature methods, 10(8), 741-743 (2013-07-03)
We report the use of clustered, regularly interspaced, short palindromic repeats (CRISPR)-associated endonuclease Cas9 to target genomic sequences in the Caenorhabditis elegans germ line using single-guide RNAs that are expressed from a U6 small nuclear RNA promoter. Our results demonstrate
Stephen J Pettitt et al.
Nature communications, 9(1), 1849-1849 (2018-05-12)
Although PARP inhibitors (PARPi) target homologous recombination defective tumours, drug resistance frequently emerges, often via poorly understood mechanisms. Here, using genome-wide and high-density CRISPR-Cas9 "tag-mutate-enrich" mutagenesis screens, we identify close to full-length mutant forms of PARP1 that cause in vitro
Thomas Gaj et al.
Trends in biotechnology, 31(7), 397-405 (2013-05-15)
Zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) comprise a powerful class of tools that are redefining the boundaries of biological research. These chimeric nucleases are composed of programmable, sequence-specific DNA-binding modules linked to a nonspecific DNA cleavage domain.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| CRISPR | 04061838113177 |
| CRISPRPL-1EA | 04061833541401 |
| HSOLIGOINT-1KT | 04061833826539 |
| CRISPR01-1SET | 04061833533802 |
| CRISPR02-1SET | 04061833533819 |
| HKCRISPR-1EA | 04061833813959 |
| PCRISPR001-1KT | 04065266925234 |
| PCRISPR002-1KT | 04065266925241 |
| CAS9D10AMRNA-1EA | 04061833531495 |
| CAS9D10AP-1EA | 04061833531501 |
| PCRISPR003-1KT | 04065266925258 |
| PCRISPR004-1EA | 04065266925265 |
| PCRISPR007-1EA | 04065266925296 |
| PCRISPR008-1EA | 04065266925302 |
| CRISPR06-1EA | 04061833533826 |
| CRISPR07-1EA | 04061833533833 |
| CRISPR08-1EA | 04061833533840 |
| CRISPR11-1EA | 04061833541265 |
| CRISPR12-1EA | 04061833541289 |