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B4252

5-Bromo-4-chloro-3-indolyl β-D-galactopyranoside

Name: 5-Bromo-4-chloro-3-indolyl &#946;-<SC>D</SC>-galactopyranoside
Brand: SIAL

chromogenic, ≥98%, powder

Synonym(s):

5-Bromo-4-chloro-3-indolyl β-D-galactoside, BCIG, X-Gal

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₁₅BrClNO₆

CAS Number:

7240-90-6

Molecular Weight:

408.63

NACRES:

NA.83

PubChem Substance ID:

24891761

UNSPSC Code:

12352204

EC Number:

230-640-8

MDL number:

MFCD00005666

Beilstein/REAXYS Number:

1402009

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Properties

Product Name

5-Bromo-4-chloro-3-indolyl β-D-galactopyranoside, ≥98%, powder

Quality Level

200

assay

≥98%

form

powder

solubility

DMF: methanol (1:1): 50 mg/mL

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](Oc2c[nH]c3ccc(Br)c(Cl)c23)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C14H15BrClNO6/c15-5-1-2-6-9(10(5)16)7(3-17-6)22-14-13(21)12(20)11(19)8(4-18)23-14/h1-3,8,11-14,17-21H,4H2/t8-,11+,12+,13-,14-/m1/s1

InChI key

OPIFSICVWOWJMJ-AEOCFKNESA-N

Description

Application

X-Gal is a chromogenic substrate for β-galactosidase that produces a rich blue color that can easily be detected visually over background. X-Gal is the substrate of choice for blue-white selection of recombinant bacterial colonies with the lac⁺ genotype.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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FAK Inhibition Induces Glioblastoma Cell Senescence-Like State through p62 and p27.

Lía Alza et al.

Cancers, 12(5) (2020-05-01)

Focal adhesion kinase (FAK) is a central component of focal adhesions that regulate cancer cell proliferation and migration. Here, we studied the effects of FAK inhibition in glioblastoma (GBM), a fast growing brain tumor that has a poor prognosis. Treating

Three-Dimensional X-ray Imaging of β-Galactosidase Reporter Activity by Micro-CT: Implication for Quantitative Analysis of Gene Expression.

Olga Ermakova et al.

Brain sciences, 11(6) (2021-07-03)

Acquisition of detailed anatomical and molecular knowledge from intact biological samples while preserving their native three-dimensional structure is still a challenging issue for imaging studies aiming to unravel a system's functions. Three-dimensional micro-CT X-ray imaging with a high spatial resolution

Therapy with Multipotent Mesenchymal Stromal Cells Protects Lungs from Radiation-Induced Injury and Reduces the Risk of Lung Metastasis.

Diana Klein et al.

Antioxidants & redox signaling, 24(2), 53-69 (2015-06-13)

Previous thorax irradiation promotes metastatic spread of tumor cells to the lung. We hypothesized that vascular damage facilitates lung metastasis after thorax irradiation and that therapeutically applied multipotent mesenchymal stromal cells (MSCs) with reported repair activity may prevent these adverse

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Global Trade Item Number

SKU	GTIN
B4252-2G	04061833616550
B4252-500MG	04061833429419
B4252-5G	04061833429426
B4252-100MG	04061835540693
B4252-150MG	04061831156461
B4252-1G	04061835480234
B4252-250MG	04061835553792
B4252-50MG	04061835553808