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Merck

COX17

COX17 cytochrome c oxidase copper chaperone

Synonyms:
Species:
Human COX17 (10063), Mouse Cox17 (12856), Rat Cox17 (89786), Zebrafish cox17 (447914), cow COX17 (100295800), dog COX17 (503668), chicken COX17 (770190), Thale Cress COX17 (820770)
UniProtKB ID:
Q14061, B2R5D2, D3DN84, Q3MHD6
Gene ID:
  • Human(10063) Summary: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provided by RefSeq, Jul 2008]
  • Mouse(12856) cytochrome c oxidase assembly protein 17
  • Rat(89786) COX17 cytochrome c oxidase copper chaperone
  • Zebrafish(447914) COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
  • cow(100295800) COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
  • dog(503668) COX17 homolog, cytochrome c oxidase assembly protein (yeast)
  • chicken(770190) COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
  • Thale Cress(820770) cytochrome c oxidase subunit XVII assembly protein

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA048158
Anti-COX17 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
HPA042226
Anti-COX17 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
EHU112711
MISSION® esiRNA, targeting human COX17,
Species
human
EMU202461
MISSION® esiRNA, targeting mouse Cox17,
Species
mouse