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Merck

An intermediate for chloroquine analogs: (E)-2-(4,7-dichloro-2-quinolinyl)-3-(dimethylamino)-2-propenal.

Acta crystallographica. Section C, Crystal structure communications (1995-07-15)
J T Mague, D De, D J Krogstad
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The title compound C14H12C12N2O, has been shown to have an E configuration about the double bond in the propenal moiety. Significant delocalization of the lone pair on the N atom of the dimethylamino group into the pi system of this moiety is indicated by the planarity about this N atom.

MATERIALS
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Sigma-Aldrich
4,7-Dichloroquinoline, 97%
Sigma-Aldrich
4,7-Dichloroquinoline, ≥99%