I1252
DL-Isocitric acid trisodium salt hydrate
≥93%
동의어(들):
threo-DsLs-Isocitric acid trisodium salt hydrate
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C6H5Na3O7 · xH2O
CAS 번호:
Molecular Weight:
258.07 (anhydrous basis)
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.25
분석
≥93%
SMILES string
O.[Na+].[Na+].[Na+].OC(C(CC([O-])=O)C([O-])=O)C([O-])=O
InChI
1S/C6H8O7.3Na.H2O/c7-3(8)1-2(5(10)11)4(9)6(12)13;;;;/h2,4,9H,1H2,(H,7,8)(H,10,11)(H,12,13);;;;1H2/q;3*+1;/p-3
InChI key
BPEHKAXIRZOKIS-UHFFFAOYSA-K
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
An-Ping Lin et al.
Biochemistry, 50(38), 8241-8250 (2011-08-25)
Yeast NAD(+)-specific isocitrate dehydrogenase is an allosterically regulated octameric enzyme composed of four heterodimers of a catalytic IDH2 subunit and a regulatory IDH1 subunit. Despite structural predictions that the enzyme would contain eight isocitrate binding sites, four NAD(+) binding sites
Alexander B Taylor et al.
The Journal of biological chemistry, 283(16), 10872-10880 (2008-02-08)
Mitochondrial NAD(+)-specific isocitrate dehydrogenases (IDHs) are key regulators of flux through biosynthetic and oxidative pathways in response to cellular energy levels. Here we present the first structures of a eukaryotic member of this enzyme family, the allosteric, hetero-octameric, NAD(+)-specific IDH
Metabolism, gliomas, and IDH1.
Jan Smeitink
The New England journal of medicine, 362(12), 1144-1145 (2010-03-26)
Mutations to metabolic enzymes in cancer herald a need to unify genetics and biochemistry.
Akane Kawamura et al.
Cell cycle (Georgetown, Tex.), 10(17), 2819-2820 (2011-08-23)
Grant C Bullock et al.
Blood, 116(1), 97-108 (2010-04-22)
Human red cell differentiation requires the action of erythropoietin on committed progenitor cells. In iron deficiency, committed erythroid progenitors lose responsiveness to erythropoietin, resulting in hypoplastic anemia. To address the basis for iron regulation of erythropoiesis, we established primary hematopoietic
프로토콜
We describe here a rapid and sensitive method to separate and measure D-2-OHG and L-2-OHG enantiomers using high-resolution mass spectrometry (HRMS) detection.
Chromatograms
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