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Merck

G1501

Sigma-Aldrich

L-Glutamic acid potassium salt monohydrate

≥99% (HPLC), powder

동의어(들):

MPG, Monopotassium glutamate, Potassium 2-amino-5-hydroxy-5-oxopentanoate, (S)-2-Aminopentanedioic acid, L-α-Aminoglutaric acid potassium salt, L-2-Aminopentanedioic acid potassium salt, Glu, Potassium L-glutamate

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C5H8KNO4 · H2O
CAS 번호:
6382-01-0
Molecular Weight:
203.23
Beilstein:
3637377
MDL number:
MFCD00150343
UNSPSC 코드:
12352209
PubChem Substance ID:
24895063
NACRES:
NA.32

주요 문서

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Quality Level

300

분석

≥99% (HPLC)

양식

powder

색상

white

SMILES string

O.[K+].N[C@@H](CCC([O-])=O)C(O)=O

InChI

1S/C5H9NO4.K.H2O/c6-3(5(9)10)1-2-4(7)8;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2/q;+1;/p-1/t3-;;/m0../s1

InChI key

XIBUKSQTWSKJMQ-QTNFYWBSSA-M

유전자 정보

human ... GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK4(2900), GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), GRINA(2907)
mouse ... GRIK1(14805), GRIK2(14806), GRIK3(14807), GRIK4(110637), GRIN1(14810), GRIN2A(14811), GRIN2B(14812), GRIN2C(14813), GRIN2D(14814), GRIN3A(242443), GRIN3B(170483), GRINA(66168)
rat ... GRIK1(29559), GRIK2(54257), GRIK3(298521), GRIK4(24406), GRIN1(24408), GRIN2A(24409), GRIN2B(24410), GRIN2C(24411), GRIN2D(24412), GRIN3A(191573), GRIN3B(170796), GRINA(266668)

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관련 카테고리

일반 설명

L-glutamate is the major excitatory neurotransmitter in mammalian central nervous system (CNS). It interacts with membrane bound glutamate receptors. Potassium -glutamate is also used as a component of MEM non-essential amino acids solution in cell culture.

애플리케이션

L-Glutamic acid potassium salt monohydrate has been used-
  • A component of MEM non-essential amino acids solution in cell culture.
  • For the purification of tubulins from bovine brain.
  • In stock solution for the preparation of quenching buffer during the formationof dual-color polarity-marked fluorescent microtubule seeds.
  • The preparation of cell free extracts devoid of RF2 (release factor 2) from Escherichia coli strains.
  • preparation of stock solutions during culture of Arabidopsis plants.

생화학적/생리학적 작용

Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.
L-glutamate plays key roles in development, learning, memory, plasticity and cognition. It plays crucial role in the pathogenesis of neuropathological diseases such as epilepsy, schizophrenia, stroke, ischemia, ALS (amyotrophic lateral sclerosis), Huntington′s disease and Parkinson′s disease. Glutamate is also responsible for the activation of long-term potentiation (LTP) and long-term depression (LTD). Induction of glutamate receptors plays a key role in the pathophysiology of migraine.

특징 및 장점

Our highly purified L-Glutamic acid potassium salt monohydrate will support your purification or preparation neuropathological diseases research needs

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
SLCM3521
SLCM3518
SLCM3515
SLCM3519
SLCL9369

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Miho Katsuki et al.
Methods in molecular biology (Clifton, N.J.), 777, 117-126 (2011-07-21)
Assaying microtubule dynamics in vitro requires stabilized nucleation centers, a method to immobilize individual microtubules onto a surface, and a specialized microscope to image the microtubule. Microtubules are polar structures with different dynamic properties at the plus and minus ends.
Nitin Shirole et al.
Journal of visualized experiments : JoVE, (48)(48), doi:10-doi:10 (2011-03-16)
Recently, structural and biochemical studies have detailed many of the molecular events that occur in the ribosome during inhibition of protein synthesis by antibiotics and during nascent polypeptide synthesis. Some of these antibiotics, and regulatory nascent polypeptides mostly in the
E D Brenner et al.
Plant physiology, 124(4), 1615-1624 (2000-12-15)
Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are the predominant neuroreceptors in the mammalian brain. Genes with high sequence similarity to animal iGluRs have been identified in Arabidopsis. To understand the role of Arabidopsis glutamate receptor-like (AtGLR) genes
Hiroaki Tani et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(4), 1288-1300 (2010-01-29)
The neurotransmitter glutamate is recycled through an astrocytic-neuronal glutamate-glutamine cycle in which synaptic glutamate is taken up by astrocytes, metabolized to glutamine, and transferred to neurons for conversion back to glutamate and subsequent release. The extent to which neuronal glutamate
Martina Curto et al.
The journal of headache and pain, 17, 47-47 (2016-05-01)
Activation of glutamate (Glu) receptors plays a key role in the pathophysiology of migraine. Both NMDA and metabotropic Glu receptors are activated or inhibited by metabolites of the kynurenine pathway, such as kynureninic acid (KYNA), quinolinic acid (QUINA), and xanthurenic
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