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Merck

C5865

Sigma-Aldrich

CD437

≥98% (HPLC), retinoic acid receptor (RAR)γ-selective agonist, solid

동의어(들):

6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid, AHPN

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C27H26O3
CAS 번호:
125316-60-1
Molecular Weight:
398.49
MDL number:
MFCD03106506
UNSPSC 코드:
12352200
PubChem Substance ID:
24724445
NACRES:
NA.77

주요 문서

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제품 이름

CD437, ≥98% (HPLC), solid

Quality Level

100

분석

≥98% (HPLC)

양식

solid

불순물

~0.5 mol/mol water

색상

yellow

mp

271.6-276 °C

solubility

DMSO: >10 mg/mL
H2O: insoluble

저장 온도

−20°C

SMILES string

OC(=O)c1ccc2cc(ccc2c1)-c3ccc(O)c(c3)C45CC6CC(CC(C6)C4)C5

InChI

1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)

InChI key

LDGIHZJOIQSHPB-UHFFFAOYSA-N

유전자 정보

human ... RARA(5914), RARB(5915), RARG(5916)

관련 카테고리

생화학적/생리학적 작용

CD437 is a retinoic acid receptor (RAR)γ-selective agonist, γ-selective retinoid; potent inducer of apoptosis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
022M4623V
068K46292
068K46291
068K4629
057K4610

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

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A variety of pathways target CDKI p21WAF1/CIP1 expression at transcriptional, post-transcriptional as well as translational levels. We previously found that cell growth suppressing retinoid CD437 enhanced expression of p21WAF1/CIP1 and DNA damage inducible GADD45 proteins in part by elevating their
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