860510P
Avanti
C10 Ceramide (d18:1/10:0)
Avanti Research™ - A Croda Brand
동의어(들):
N-decanoyl-D-erythro-sphingosine
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C28H55NO3
CAS 번호:
Molecular Weight:
453.74
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25
제품 이름
C10 Ceramide (d18:1/10:0), Avanti Research™ - A Croda Brand 860510P, powder
분석
>99% (TLC)
양식
powder
포장
pkg of 1 × 5 mg (860510P-5mg)
제조업체/상표
Avanti Research™ - A Croda Brand 860510P
지질 유형
sphingolipids
배송 상태
dry ice
저장 온도
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C28H55NO3/c1-3-5-7-9-11-12-13-14-15-16-18-19-21-23-27(31)26(25-30)29-28(32)24-22-20-17-10-8-6-4-2/h21,23,26-27,30-31H,3-20,22,24-25H2,1-2H3,(H,29,32)/b23-21+/t26-,27+/m0/s1
InChI key
FDWVAQFAMZLCAX-NBNLIBPQSA-N
일반 설명
C10 Ceramide (d18:1/10:0) is a synthetic ceramide containing sphingosine with decanoic acid. It has a short acyl chain length than sphingosine acyl chain.
애플리케이션
C10 Ceramide (d18:1/10:0) or N-decanoyl-D-erythro-sphingosine has been used:
- as an internal standard in galactocerebrosidase (GALC) assay
- to study its role on the physical properties of edible organogels and on their ability to induce cell death of various cancer cell lines
- to study its mixing behavior with other ceramides having the same sphingosine base but varying N-linked acyl chain length
생화학적/생리학적 작용
Ceramides modulate stress responses and inflammation. It also controls cell differentiation, proliferation and apoptosis.
포장
5 mL Amber Glass Screw Cap Vial (860510P-5mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Meenu N Perera et al.
Chemistry and physics of lipids, 194, 110-116 (2015-09-27)
A ceramide commonly found in mammalian cells, C16-ceramide (N-palmitoyl-d-erythro-sphingosine), is capable of forming large, protein-permeable channels in the mitochondrial outer membrane (MOM). However, C16-ceramide is unable to permeabilize the plasma membrane of erythrocytes. This specificity is unexpected considering that ceramide
Zhixing Wang et al.
The Journal of investigative dermatology, 133(3), 668-676 (2012-10-26)
The stratum corneum is composed of protein-enriched corneocytes embedded in an intercellular matrix of nonpolar lipids organized as lamellar layers and giving rise to epidermal permeability barrier (EPB). EPB defects have an important role in the pathophysiology of skin diseases
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