103799
Pentafluorophenol
≥99%, for peptide synthesis, ReagentPlus®
동의어(들):
2,3,4,5,6-Pentafluorophenol
로그인조직 및 계약 가격 보기
크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
C6F5OH
CAS 번호:
Molecular Weight:
184.06
Beilstein:
1912584
EC Number:
MDL number:
UNSPSC 코드:
12352104
PubChem Substance ID:
NACRES:
NA.22
제품 이름
Pentafluorophenol, ReagentPlus®, ≥99%
Quality Level
제품 라인
ReagentPlus®
분석
≥99%
양식
solid
bp
143 °C (lit.)
mp
34-36 °C (lit.)
응용 분야
peptide synthesis
작용기
fluoro
SMILES string
Oc1c(F)c(F)c(F)c(F)c1F
InChI
1S/C6HF5O/c7-1-2(8)4(10)6(12)5(11)3(1)9/h12H
InChI key
XBNGYFFABRKICK-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Pentafluorophenol is widely used as a precursor in both solution and solid-phase peptide synthesis. It is also involved in the preparation of aromatic fluoro derivatives.
애플리케이션
Pentafluorophenol can be used as a reactant to synthesize pentafluorophenyl esters from:
- N-protected amino acid in the presence of dicyclohexylcarbodiimide and ethyl acetate.
- t-Butoxycarbonyl-L-alanylglycinein the presence of 1-ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride.
- Aliphatic dicarboxylic acids in the presence of pyridine, diisopropylcarbodiimide, and acetonitrile.
법적 정보
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
161.6 °F - closed cup
Flash Point (°C)
72 °C - closed cup
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
Pentafluorophenol
Jones K
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2001)
M Adamczyk et al.
Bioconjugate chemistry, 8(2), 253-255 (1997-03-01)
A mixture of 5- and 6-carboxyfluorescein was activated with 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide hydrochloride in the presence of either N-hydroxysuccinimide or pentafluorophenol to give the corresponding succinimidyl and pentafluorophenyl esters. The regioisomeric mixtures were separated to give the 5- and 6-succinimidyl and pentafluorophenyl
Nadine Grebenstein et al.
Journal of chromatography. A, 1243, 39-46 (2012-05-09)
Of the eight natural vitamin E congeners (α-, β-, γ-, and δ-tocopherol and α-, β-, γ-, and δ-tocotrienol), the non-α-tocopherol congeners have unique biological properties that may contribute to human health. Their study in vivo has been complicated by the
Nicolas Abello et al.
Analytical chemistry, 80(23), 9171-9180 (2008-10-29)
Stable isotope labeling (SIL) in combination with liquid chromatography-mass spectrometry is one of the most widely used quantitative analytical methods due to its sensitivity and ability to deal with extremely complex biological samples. However, SIL methods for metabolite analysis are
Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3.
K C Nicolaou et al.
Angewandte Chemie (International ed. in English), 45(16), 2609-2615 (2006-03-21)
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