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About This Item
Empirical Formula (Hill Notation):
C35H71N2O6P
CAS Number:
Molecular Weight:
646.92
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
12:0 SM (d18:1/12:0), Avanti Research™ - A Croda Brand 860583P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860583P-10mg), pkg of 1 × 25 mg (860583P-25mg), pkg of 1 × 5 mg (860583P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860583P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O
InChI
1S/C35H71N2O6P/c1-6-8-10-12-14-16-17-18-19-21-22-24-26-28-34(38)33(32-43-44(40,41)42-31-30-37(3,4)5)36-35(39)29-27-25-23-20-15-13-11-9-7-2/h26,28,33-34,38H,6-25,27,29-32H2,1-5H3,(H-,36,39,40,41)/b28-26+/t33-,34+/m0/s1
InChI key
HZCLJRFPXMKWHR-FEBLJDHQSA-N
Application
12:0 SM (d18:1/12:0) has been used:
- as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions
- as an internal standard for the quantification of serum cholesterol and triacylglycerol using liquid chromatography-mass spectrometry (LC-MS) preceded by single-step liquid-liquid extraction method
- as an internal standard for tandem mass spectrometry analysis of lipid species
Packaging
5 mL Amber Glass Screw Cap Vial (860583P-10mg)
5 mL Amber Glass Screw Cap Vial (860583P-25mg)
5 mL Amber Glass Screw Cap Vial (860583P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
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Ursula Loizides-Mangold et al.
Journal of lipid research, 53(8), 1522-1534 (2012-05-26)
Glycosylphosphatidylinositol (GPI) anchor biosynthesis takes place in the endoplasmic reticulum (ER). After protein attachment, the GPI anchor is transported to the Golgi where it undergoes fatty acid remodeling. The ER exit of GPI-anchored proteins is controlled by glycan remodeling and
Jinfeng Huang et al.
Dose-response : a publication of International Hormesis Society, 18(2), 1559325820914209-1559325820914209 (2020-05-05)
Radiation biodosimeters are required urgently for fast and accurate evaluation of absorbed dose for irradiated individuals. Lipidomics has appeared as a credible technique for identification and quantification of lipid for researching biomarker of diseases. We performed a lipidomic profile on
Elisabeth Corcelle-Termeau et al.
Autophagy, 12(5), 833-849 (2016-04-14)
Sphingomyelin is an essential cellular lipid that traffics between plasma membrane and intracellular organelles until directed to lysosomes for SMPD1 (sphingomyelin phosphodiesterase 1)-mediated degradation. Inactivating mutations in the SMPD1 gene result in Niemann-Pick diseases type A and B characterized by
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 860583P-10MG | 04061835318261 |
| 860583P-25MG | 04061835318278 |
| 860583P-5MG | 04061835318285 |