Glycoconjugates

Glycoconjugates consist of carbohydrates, or glycans, linked to a protein, lipid, peptide, and other compounds. Glycoconjugates are formed by glycosylation and are involved in various biological processes in organisms. Glycobiology research studies the structure and activity of carbohydrates and glycoconjugates in relation to human health. Understanding how disorders in these processes lead to severe diseases is also relevant to molecular and cellular biology, proteomics, and medicine.
We offer a comprehensive portfolio of glycoconjugates including glycolipids, glycoproteins, and lipopolysaccharides for all your research needs, including extraction, characterization, formulation, chemical/enzymatic modifications involving non-conventional media or activation modes. Discover drug targets for infectious diseases, inflammation, and cancer; develop new potential vaccines against cancer, viral and bacterial infections, and other diseases; and explore other potential uses of glycoconjugates as therapeutics.
Products
Related Resources
- Article: BIOshell Glycan HPLC ColumnsFast, high-resolution separations of procainamide labeled glycans - dextran ladder, human IgG and cetuximab 
- Article: Deglycosylation KitsDeglycosylation Kits 
- Article: Enzymatic DeglycosylationEnzymatic Deglycosylation Strategies: Sequential hydrolysis of individual monosaccharides from glycans can be useful for the elucidation of the structure and function of the glycan component. 
- Article: Glycoprotein DeglycosylationInformation about Glycoprotein deglycosylation. The diversity of oligosaccharide structures, both O-linked and N-linked, often results in heterogeneity in the mass and charge of glycoproteins. 
- Article: Glycosaminoglycans and ProteoglycansThere are five identified glycosaminoglycan chains (see Figure 1): Hyaluronan is not sulfated, but the other glycosaminoglycan chains contain sulfate substituents at various positions of the chain. 
- Article: GlycosphingolipidsGlycosphingolipids 
- Article: GPI Anchored GlycoproteinsGPI Anchored Glycoproteins 
- Article: LipopolysacharidesLipopolysaccharide (LPS) is the major component of the outer membrane of Gram-negative bacteria. Lipopolysaccharide is localized in the outer layer of the membrane and is, in noncapsulated strains, exposed on the cell surface. 
- Article: PeptidoglycansThe basic structure of peptidoglycan (PGN) contains a carbohydrate backbone of alternating units of N-acetylglucosamine (GlcNAc) and Nacetylmuramic acid, with the N-acetylmuramic acid residues cross-linked to peptides. 
- Article: Purification and Removal of Glycoproteins and Polysaccharides
- Article: Strategies for Deglycosylating N-linked GlycansExplore various strategies for deglycosylating N-linked glycans involving PNGase F, PNGase A (Glycopeptidase A), and even native and sequential deglycosylation with endoglycosidases like Endoglycosidase H, Endoglycosidase F, and exoglycosidases. 
- Brochure: GlycobiologyGlycobiology and glycoproteomics are crucial in life science, with diverse glycoproteins and important roles in cellular communication and physiology. 
- Brochure: Glycoconjugates from GlycoNZGlycobiology is vital in understanding carbohydrates' role in human health. We offer a wide range of products, including glycoconjugates, and have expanded our portfolio through a partnership with GlycoNZ, offering more opportunities for exploring drug targets for various diseases. 
- Selection Guide: DeglycosylationComplete kits for highly specific deglycosylation. 
- Selection Guide: Glycoproteomics Selection Guide — DeglycosylationGlycoproteomics Selection Guide — Deglycosylation and Glycoproteomics Selection Guide — Labeling and Detection, Quantitation 
To continue reading please sign in or create an account.
Don't Have An Account?