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P5648

β-Propiolactone

Grade II, ≥90%

Synonym(s):

Oxetan-2-one, 3-Hydroxypropionic acid lactone, Hydracrylic acid β-lactone

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About This Item

Empirical Formula (Hill Notation):
C3H4O2
CAS Number:
57-57-8
Molecular Weight:
72.06
NACRES:
NA.77
PubChem Substance ID:
24898684
UNSPSC Code:
12352103
EC Number:
200-340-1
MDL number:
MFCD00005169
Assay:
≥90%
Quality level:
200
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type

Grade II

Quality Level

200

assay

≥90%

refractive index

n20/D 1.412 (lit.)

bp

162 °C (lit.)

mp

−33 °C (lit.)

density

1.146 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

O=C1CCO1

InChI

1S/C3H4O2/c4-3-1-2-5-3/h1-2H2

InChI key

VEZXCJBBBCKRPI-UHFFFAOYSA-N

General description

β-Propiolactone is an alkylating agent which is mainly used in veterinary vaccines. It will not interfere with the antigenicity of vaccine.

Application

β-Propiolactone has been used for Influenza virus deactivation.

Disclaimer

Insoluble polymers may form during storage.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

158.0 °F - closed cup

flash_point_c

70 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

57-57-8

CAS No.

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Certificates of Analysis (COA)

Lot/Batch Number
019K1200
108K1658
048K1047
S54087
071K1561

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Vesla I Kullaya et al.
Viral immunology, 30(8), 576-581 (2017-08-08)
Detection of respiratory syncytial virus (RSV) in blood, including mononuclear leukocytes and organs other than the lung, suggests that RSV disseminates outside the respiratory tract. In this study, the role of platelets in host defense against RSV was explored using
Wei Zhang et al.
Viruses, 11(7) (2019-07-11)
To date, there is no licensed vaccine available to prevent respiratory syncytial virus (RSV) infection. The valuable pre-fusion conformation of the fusion protein (pre-F) is prone to lose high neutralizing antigenic sites. The goals of this study were to stabilize
Veterinary Immunology-E book, 262-262 (2013)
View All Related Papers

Global Trade Item Number

SKUGTIN
P5648-10ML04061838164629
P5648-100ML04061838164612
P5648-1ML04061838164636
P5648-50ML04061838114556
P5648-5ML04061838092823