Skip to Content
Merck

Key Documents

View All Documentation

A6582

Antifoam A concentrate

active silicone polymer 100%

Synonym(s):

Antifoam agent, Antifoam solution, Foam control agent

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

NACRES:
NA.85
UNSPSC Code:
12161901
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

200

form

emulsion (aqueous)

technique(s)

cell culture | hybridoma: suitable, microbiological culture: suitable

density

0.97 g/mL at 25 °C

application(s)

microbiology

storage temp.

room temp

suitability

(Mammalian (suspension)), bacteria (fermentation)

General description

Antifoam A is a silicone-based product used to prevent or minimize foaming in both microbial fermentation systems and mammalian suspension cultures. Control of foaming minimizes damage to the cells, resulting in increased protein/antibody production. Extremely effective for aqueous and non-aqueous systems. Effective at concentrations in the 1-50ppm range.

Application

Antifoam A concentrate has been used:
  • in bioreactor culture for Staphylococcal enterotoxin C (SEC) production.
  • to prevent foam formation during the aerobic treatment of sludge.
  • to study the impact of surface tension on bioaerosol generation during bubbling.

Features and Benefits

  • Molecular biology grade and tested for use in bacterial fermentation.
  • Extremely effective foam suppressor for aqueous and non-aqueous systems.
  • Made of 100% active silicone polymer, free of emulsifiers.
  • Typically, effective at 1-100 ppm.
  • Product will be stable in the pH range of 5 to 9.
  • Can be directly added to a fermentation medium but it is not recommended that it be pumped to a fermenter on an as-needed basis.

Preparation Note

Antifoam A can be pre-diluted with 3-10 parts of aqueous propylene glycol or non-aqueous vegetable oil with slow mixing.

Other Notes

Antifoam A is a 100% active silicon polymer containing no non-ionic emulsifiers .

Still not finding the right product?

Explore all of our products under Antifoam A concentrate

pictograms

Environment
GHS09

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

>213.8 °F - closed cup

flash_point_c

> 101 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - PBT - vPvB

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

556-67-2 + 541-02-6

CAS No.

541-02-6

CAS No.

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
126K0084
124K0118
073K0672
072K1389
061K141515

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

M Schlömann et al.
Journal of bacteriology, 172(9), 5119-5129 (1990-09-01)
Enzymatic conversion of 4-fluorocatechol in the simultaneous presence of partially purified preparations of catechol 1,2-dioxygenase from Pseudomonas cepacia and muconate cycloisomerase from Alcaligenes eutrophus 335 yielded a product that was unambiguously identified as (+)-4-fluoromuconolactone [(+)-4-carboxymethyl-4-fluoro-but-2-en-4-olide]. This compound was shown to
F P Ernani et al.
Infection and immunity, 61(6), 2596-2601 (1993-06-01)
Substantial evidence indicates that molecules released by infectious organisms affect virulence and influence immunity to infection. The characterization of extracellular molecules and their mechanism of release is therefore critical to understanding host-parasite relationships. The cestode parasite Mesocestoides corti is known
Experience with a perfo-suction system for the recovery of schistosomes from laboratory rodents
T. F. H. G. Jackson, C. D. Dettman, et al.
Laboratory Animal Science, 16, 65-67 (1982)
View All Related Papers

Global Trade Item Number

SKUGTIN
A6582-100G04061833382516