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LM1701

Avanti

17:1 Lyso PA

Avanti Research™ - A Croda Brand

Synonym(s):

1-(10Z-heptadecenoyl)-sn-glycero-3-phosphate (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C20H42NO7P
CAS Number:
1246298-35-0
Molecular Weight:
439.52
UNSPSC Code:
51191904
NACRES:
NA.25
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assay

>99% (TLC)

form

methanol solution

packaging

pkg of 1 × 1 mL (LM1701-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

~10 μg/mL (Refer to C of A for lot specific concentration. )

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O.[NH4+]

InChI

1S/C20H39O7P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(22)26-17-19(21)18-27-28(23,24)25;/h7-8,19,21H,2-6,9-18H2,1H3,(H2,23,24,25);1H3/b8-7-;/t19-;/m1./s1

InChI key

LBIQHMMMFNLTFC-FROQVYCJSA-N

General description

Lysophosphatidic acid (Lyso PA) is a water-soluble lipid, localized to all cells and tissues in mammals.

Application

17:1 Lyso PA or 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphate (ammonium salt) has been used as an internal standard for unsaturated lysophosphatidic acid (LPA) ester and cyclic LPA ethers in reversed-phase ultra-performance liquid chromatography-tandem mass spectrometry (UPLC/MS/MS).

Biochem/physiol Actions

Lysophosphatidic acid (Lyso PA) is considered as a biological modulator of various functions in the cell. It is a potent signaling molecule with growth-factor-like actions. Lyso PA regulates cell proliferation, survival, cytoskeletal modification and calcium influx. It is associated with smooth-muscle contraction and platelet aggregation. It is also known to regulate blood pressure. Lyso PA possess extensive biological actions and is involved in the progression of several human cancer.

Packaging

2 mL Amber Glass Sealed Ampule (LM1701-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

67-56-1

CAS No.

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Gordon B Mills et al.
Nature reviews. Cancer, 3(8), 582-591 (2003-08-02)
The bioactive phospholipid lysophosphatidic acid (LPA) stimulates cell proliferation, migration and survival by acting on its cognate G-protein-coupled receptors. Aberrant LPA production, receptor expression and signalling probably contribute to cancer initiation, progression and metastasis. The recent identification of ecto-enzymes that

Global Trade Item Number

SKUGTIN
LM1701-1EA04061837669750