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C3416

Carbénicilline disodium salt

Name: Carbénicilline disodium salt
Brand: SIGMA

BioReagent, suitable for plant cell culture

Synonyme(s) :

α-Carboxybenzylpénicilline disodium salt

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A propos de cet article

Formule empirique (notation de Hill) :

C₁₇H₁₆N₂Na₂O₆S

Numéro CAS:

4800-94-6

Poids moléculaire :

422.36

UNSPSC Code:

51282413

NACRES:

NA.76

PubChem Substance ID:

24892613

EC Number:

225-360-8

Beilstein/REAXYS Number:

5722128

MDL number:

MFCD00077683

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Propriétés

product line

BioReagent

Quality Level

200

form

powder

technique(s)

cell culture | plant: suitable

solubility

H₂O: 50 mg/mL

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

application(s)

agriculture

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)c3ccccc3)C(=O)N2[C@H]1C([O-])=O

InChI

1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1

InChI key

RTYJTGSCYUUYAL-YCAHSCEMSA-L

Description

General description

Chemical structure: β-lactam

Application

Recommended for antibacterial use in cell culture media at 100 μg/ml and for selection of ampr transformed cells.

Biochem/physiol Actions

Mode d'action : Ce produit est un antibiotique du type carboxypénicilline qui inhibe la synthèse de la paroi cellulaire chez les bactéries (réticulation du peptidoglycane) en inactivant les transpeptidases situées sur la face interne de la membrane cellulaire.

Spectre antimicrobien : Produit actif contre les bactéries à Gram positif et à Gram négatif

Physical form

Hygroscopic powder

Analysis Note

Produit stable pendant trois jours à 37 °C.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.

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pictograms

GHS08

signalword

Danger

hcodes

H317,H334

pcodes

P261 - P280 - P342 + P311

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Classe de stockage

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number

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Protocoles

Antibiotics in Plant Tissue Culture Protocol

Reference guide and preparation guide for antibiotic and antimycotic use in plant tissue culture.

Articles

Antibiotic Kill Curve

Antibiotic kill curve is a dose response experiment in which mammalian cells are subjected to increasing amounts of selection antibiotic

Contenu apparenté

Antibiotics and Antimycotics

Product Information Sheet - C3416

Inactivation of MuxABC-OpmB transporter system in Pseudomonas aeruginosa leads to increased ampicillin and carbenicillin resistance and decreased virulence.

Liang Yang et al.

Journal of microbiology (Seoul, Korea), 49(1), 107-114 (2011-03-04)

Resistance-Nodulation-Cell Division (RND) pumps play important roles in bacterial resistance to antibiotics. Pseudomonas aeruginosa is an important human pathogen which exhibits high level resistance to antibiotics. There are total of 12 RND pumps present in the P. aeruginosa PAOl genome.

Molecular dynamics of class A β-lactamases-effects of substrate binding.

Olivier Fisette et al.

Biophysical journal, 103(8), 1790-1801 (2012-10-23)

The effects of substrate binding on class A β-lactamase dynamics were studied using molecular dynamics simulations of two model enzymes; 40 100-ns trajectories of the free and substrate-bound forms of TEM-1 (with benzylpenicillin) and PSE-4 (with carbenicillin) were recorded (totaling

Pseudomonas aeruginosa increases formation of multidrug-tolerant persister cells in response to quorum-sensing signaling molecules.

Nina Möker et al.

Journal of bacteriology, 192(7), 1946-1955 (2010-01-26)

Bacterial persister cells constitute a small portion of a culture which is tolerant to killing by lethal doses of bactericidal antibiotics. These phenotypic variants are formed in numerous bacterial species, including those with clinical relevance like the opportunistic pathogen Pseudomonas

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Numéro d'article de commerce international

Référence	GTIN
C3416-250G	04061833690079
C3416-10G	04061833485811
C3416-1G	04061833485828
C3416-250MG	04061833485835
C3416-5G	04061835543342