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MilliporeSigma

B7639

(+)-Biotin hydrazide

≥97% (TLC), powder

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A propos de cet article

Formule empirique (notation de Hill) :
C10H18N4O2S
Numéro CAS:
Poids moléculaire :
258.34
UNSPSC Code:
12352203
NACRES:
NA.46
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
28347
Assay:
≥97% (TLC)
Form:
powder
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Quality Level

assay

≥97% (TLC)

form

powder

solubility

DMSO: ≤20 mg/mL

storage temp.

2-8°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(=O)NN)[C@@]1([H])NC(=O)N2

InChI

1S/C10H18N4O2S/c11-14-8(15)4-2-1-3-7-9-6(5-17-7)12-10(16)13-9/h6-7,9H,1-5,11H2,(H,14,15)(H2,12,13,16)/t6-,7-,9-/m0/s1

InChI key

KOZWHQPRAOJMBN-ZKWXMUAHSA-N

General description

Biotin hydrazide is a biotinylation reagent used to biotinylate glycoproteins with their sugar moieties. Biotin hydrazide can be used to prepare biotin-conjugated alginate. It can also be used for covalent attachment to PAAc via carbodi-imide cross linking.

Application

(+)-Biotin hydrazide has been used:
  • the modification of alginate
  • for the labelling of mitochondrial proteins from non-muscle tissues
  • as a component of glycoprotein staining solution
  • in periodic acid-biotin-hydrazide (PABH) assay for mucins
  • for labeling surface functional groups, biologically active molecules such as antibodies, lectins, sugars, nucleic acids or molecules with free carboxylic or keto groups.
  • for coupling to glycoproteins through the carbohydrate by hydrazone formation

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Impact of Bioactive Peptides on Human Health, 157-157 (2016)
E P Diamandis et al.
Clinical chemistry, 37(5), 625-636 (1991-05-01)
The biotin-(strept)avidin system has been used for many years in a variety of different applications. Here we present a general overview of the system, describe its components and advantages, and show how the system is used in various applications, with
Emma Luong-Van et al.
Biointerphases, 4(2), 13-18 (2010-04-23)
The spatial control of cells on a surface and the patterning of multiple cell types is an important tool for fundamental biological research and tissue engineering applications. A novel technique is described for the controlled seeding of multiple cell types



Numéro d'article de commerce international

RéférenceGTIN
B7639-1G04061826688502
B7639-100MG04061833442029