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A propos de cet article
Formule empirique (notation de Hill) :
C19H19N7O6
Numéro CAS:
Poids moléculaire :
441.40
EC Number:
200-419-0
UNSPSC Code:
41116107
NACRES:
NA.24
Beilstein/REAXYS Number:
100781
MDL number:
Service technique
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Laissez-nous vous aiderbiological source
synthetic
grade
pharmaceutical primary standard
agency
EP
API family
folic acid
form
solid
manufacturer/tradename
EDQM
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O
InChI
1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
InChI key
OVBPIULPVIDEAO-LBPRGKRZSA-N
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Folic acid, a water-soluble B vitamin, is found in several food products. As it is not generated naturally in the human body, diet is one of the easiest ways to obtain it. It plays a crucial role in the biochemical synthesis and repair of DNA and is used in the management of megaloblastic anemias, neural tube defects such as anencephaly and spina bifida. Pharmaceutical drug forms of folic acid are desirable for supplementing its consumption through the diet.
Folic acid, a water-soluble B vitamin, is found in several food products. As it is not generated naturally in the human body, diet is one of the easiest ways to obtain it. It plays a crucial role in the biochemical synthesis and repair of DNA and is used in the management of megaloblastic anemias, neural tube defects such as anencephaly and spina bifida. Pharmaceutical drug forms of folic acid are desirable for supplementing its consumption through the diet.
Application
Folic acid for impurity I identification may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
Classe de stockage
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Folic acid hydrate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 6(9), 5662-5663 (2018)
A UV spectrophotometric method for the determination of folic acid in pharmaceutical tablets and dissolution tests
Matias R, et al.
Analytical Methods : Advancing Methods and Applications, 6(9), 3065-3071 (2014)
Flow injection chemiluminometric determination of folic acid in pharmaceutical formulations
Al-Warthan.AA
Analytical Sciences, 10(6), 919-922 (1994)