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P9380

Pyridoxamine dihydrochloride

analytical standard, ≥98%

Synonyme(s) :

4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol dihydrochloride

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A propos de cet article

Formule empirique (notation de Hill) :
C8H12N2O2 · 2HCl
Numéro CAS:
Poids moléculaire :
241.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
208-357-6
Beilstein/REAXYS Number:
3632748
MDL number:
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biological source

synthetic (organic)

Quality Level

grade

analytical standard

assay

≥98%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

color

white to off-white

mp

224-226 °C (dec.) (lit.)

application(s)

vitamins, nutraceuticals, and natural products

format

neat

storage temp.

−20°C

SMILES string

Cl[H].Cl[H].Cc1ncc(CO)c(CN)c1O

InChI

1S/C8H12N2O2.2ClH/c1-5-8(12)7(2-9)6(4-11)3-10-5;;/h3,11-12H,2,4,9H2,1H3;2*1H

InChI key

HNWCOANXZNKMLR-UHFFFAOYSA-N

General description

Pyridoxamine dihydrochloride is a salt and amine form of pyridoxamine, which belongs to the family of vitamin B6 compounds. Pyridoxamine occurs naturally in animal-based food products. Its deficiency in humans potentially causes sideroblastic anemia, weakness, insomnia, and neurological disorders. It has been reported to be effective against diabetic nephropathy.

Application

Pyridoxamine dihydrochloride analytical standard can be used as follows:
  • Combined analysis of eight water-soluble vitamins along with their different forms by liquid chromatography combined with isotope-dilution mass spectrometry (IDMS) in different fortified food samples
  • Simultaneous determination of eleven water-soluble B vitamins by liquid chromatography-tandem mass spectrometry (LC-MS/MS) in ultrafiltrate samples
  • Multi-residue analysis of total thiamine, total riboflavin, total pyridoxine, and total niacin in infant formula and related nutritional products by enzymatic digestion followed by LC-MS-MS determination as per AOAC Official Method 2015.14
  • LC/MS-MS based assay of seven different vitamers of vitamin B3 and vitamin B6 in 40 human hair samples

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


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Classe de stockage

11 - Combustible Solids

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Pyridoxamine dihydrochloride in diabetic nephropathy (PIONEER-CSG-17): lessons learned from a pilot study
Dwyer JP, et al.
Nephron, 129(1), 22-28 (2015)
Nutritional diseases
Tropical Dermatology E-Book, 407-407 (2016)
Mechanisms and regulation of intestinal absorption of water-soluble vitamins: cellular and molecular aspects
Physiology of the Gastrointestinal Tract, 407-407 (2016)



Numéro d'article de commerce international

RéférenceGTIN
P9380-1G04061834402923
P9380-25G04061833653074
P9380-5G04061835564392