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8.17076

TWEEN® 60 (Polysorbate)

EMPROVE® ESSENTIAL, Ph. Eur., JPE, NF

Synonyme(s) :

Polyoxyethylene sorbitan monostearate

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A propos de cet article

Numéro CAS:
9005-67-8
UNSPSC Code:
12352104
EC Index Number:
500-020-4
MDL number:
MFCD01780110
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Quality Level

500

agency

JPE, NF, Ph. Eur.

vapor pressure

<10 hPa ( 20 °C)

product line

EMPROVE® ESSENTIAL

form

viscous liquid

technique(s)

API processing | nano-milling: suitable

pH

4,0-7.7 (25 °C, 50 g/L in H2O)

kinematic viscosity

170-320 cSt(40 °C)

transition temp

flash point >149 °C

density

1.1 g/cm3 at 20 °C

application(s)

liquid formulation
ophthalmics
pharma/biopharma processes
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement

storage temp.

15-25°C

SMILES string

O1C(C(C(C1)OCCO)OCCO)C(OCCO)COCCOC(=O)CCCCCCCCCCC

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polysorbate 60 is used as surfactant in a variety of liquid formulations and acts e.g. as emulsifying, solubilizing and wetting agent.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
TWEEN is a registered trademark of Croda International PLC

Classe de stockage

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificats d'analyse (COA)

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Articles

Strategies for the Development of Safe and Effective Pediatric Formulations

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

Contenu apparenté

Pediatric Formulations

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

Numéro d'article de commerce international

RéférenceGTIN
817076250004022536685212
817076905004022536975146