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860512P

Avanti

C12 Ceramide (d18:1/12:0)

Avanti Research - A Croda Brand

Synonyme(s) :

N-lauroyl-D-erythro-sphingosine

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A propos de cet article

Formule empirique (notation de Hill) :
C30H59NO3
Numéro CAS:
Poids moléculaire :
481.79
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (860512P-10mg), pkg of 1 × 25 mg (860512P-25mg), pkg of 1 × 5 mg (860512P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C30H59NO3/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-29(33)28(27-32)31-30(34)26-24-22-20-17-12-10-8-6-4-2/h23,25,28-29,32-33H,3-22,24,26-27H2,1-2H3,(H,31,34)/b25-23+/t28-,29+/m0/s1

InChI key

HXFPPRPLRSPNIB-VARSQMIESA-N

General description

C12 Ceramide (d18:1/12:0) is a synthetic ceramide containing sphingosine with lauric acid.

Application

C12 Ceramide (d18:1/12:0) or N-lauroyl-D-erythro-sphingosine has been used:
  • as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions
  • as an internal standard for lipid extraction in U87MG (human glioma cell line)
  • as an internal standard for the quantification of ceramide using liquid chromatography-mass spectrometry (LC-MS) in rat tissues

Biochem/physiol Actions

Ceramides are signaling sphingolipids, which are implicated in regulating stress responses and inflammation. It also regulates cell growth arrest, differentiation and apoptosis.

Packaging

5 mL Amber Glass Screw Cap Vial (860512P-10mg)
5 mL Amber Glass Screw Cap Vial (860512P-25mg)
5 mL Amber Glass Screw Cap Vial (860512P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


Classe de stockage

11 - Combustible Solids

wgk

WGK 3



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Consulter la Bibliothèque de documents



Gergely Karsai et al.
The Journal of biological chemistry, 295(7), 1889-1897 (2019-12-22)
Sphingolipids (SLs) are structurally diverse lipids that are defined by the presence of a long-chain base (LCB) backbone. Typically, LCBs contain a single Δ4E double bond (DB) (mostly d18:1), whereas the dienic LCB sphingadienine (d18:2) contains a second DB at
Mónica Narváez-Rivas et al.
Journal of chromatography. A, 1440, 123-134 (2016-03-02)
The goal of untargeted lipidomics is to have high throughput, yet comprehensive and unambiguous identification and quantification of lipids. Novel stationary phases in LC separation and new mass spectrometric instruments capable of high mass resolving power and faster scanning rate
Sonia Hernández-Tiedra et al.
Autophagy, 12(11), 2213-2229 (2016-11-02)
Autophagy is considered primarily a cell survival process, although it can also lead to cell death. However, the factors that dictate the shift between these 2 opposite outcomes remain largely unknown. In this work, we used Δ9-tetrahydrocannabinol (THC, the main



Numéro d'article de commerce international

RéférenceGTIN
860512P-25MG04061835317516
860512P-10MG04061835317509
860512P-5MG04061835317523