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A propos de cet article
Formule empirique (notation de Hill) :
C24H46O9PNa
Numéro CAS:
Poids moléculaire :
532.58
MDL number:
NACRES:
NA.25
UNSPSC Code:
51191904
Service technique
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18:1 Lyso PG, 1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform
assay
>99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC)
form
liquid
packaging
pkg of 5 × 4 mL (858125C-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 858125C
concentration
25 mg/mL (858125C-500mg)
shipped in
dry ice
storage temp.
−20°C
General description
18:1 Lyso phosphoglycerol is a lyso-phospholipid detergent. Lyso-phospholipids are produced in γ-proteobacteria by lipoprotein acyltransferase activity. These lipids are found in minimal amount in normal bacterial membranes.
Application
18:1 Lyso PG has been used as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions.
Biochem/physiol Actions
Lyso phosphoglycerol (Lyso PG) and acyl-CoA acts as a substrate for lysophosphatidylglycerol acyltransferase 1 (LPGAT1) to synthesize phosphoglycerol. Lyso-phospholipids are nonbilayer-forming lipids. Accumulation of lysophospholipids in bacterial membranes disrupt the membrane integrity due to its detergent- like physical property.
Packaging
5 mL Clear Glass Sealed Ampule (858125C-500mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
Classe de stockage
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
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Expression, purification and reconstitution of the C-terminal transmembrane domain of scavenger receptor BI into detergent micelles for NMR analysis
Chadwick A, et al.
Protein Expression and Purification, 107, 35-42 (2015)
Substrate selectivity of lysophospholipid transporter LplT involved in membrane phospholipid remodeling in Escherichia coli
Lin Y, et al.
The Journal of Biological Chemistry, 291(5), 2136-2149 (2016)
Hideo Shindou et al.
The Journal of biological chemistry, 284(1), 1-5 (2008-08-23)
Cell membranes contain several classes of glycerophospholipids, which have numerous structural and functional roles in the cells. Polyunsaturated fatty acids, including arachidonic acid and eicosapentaenoic acid, are located at the sn-2 (but not sn-1)-position of glycerophospholipids in an asymmetrical manner.
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| 858125C-500MG | 04061837793301 |