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840039P

Avanti

18:0-18:1 PS

Avanti Research™ - A Croda Brand

Synonyme(s) :

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); SOPS; PS(18:0/18:1(9Z)); 110672

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A propos de cet article

Formule empirique (notation de Hill) :
C42H79NO10PNa
Numéro CAS:
321883-23-2
Poids moléculaire :
812.04
UNSPSC Code:
51191904
NACRES:
NA.25
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Nom du produit

18:0-18:1 PS, 1-stearoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840039P-10mg), pkg of 2 × 100 mg (840039P-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840039P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C42H80NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h18,20,38-39H,3-17,19,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b20-18-;/t38-,39+;/m1./s1

InChI key

ALPKKMIPHGSQRX-NJZWBUMZSA-M

General description

18:0-18:1 PS (1-stearoyl-2-oleoyl-sn-glycero-3-phospho-L-serine) is a sodium salt of a modified lipid which has phosphoserine as the backbone.

Application

18:0-18:1 PS (1-stearoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt)):
  • has been used in the preparation of multilamellar and unilamellar liposomes
  • may be used in the preparation of liposomes for liposome binding assays
  • may be used to generate multilamellar phospholipid vesicles

Biochem/physiol Actions

Phosphatidylserine (PS) plays a key role in protein kinase C pathways.

Packaging

5 mL Clear Glass Sealed Ampule (840039P-10mg)
5 mL Clear Glass Sealed Ampule (840039P-200mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Julie K Freed et al.
Endothelium : journal of endothelial cell research, 15(4), 225-230 (2008-07-30)
Previous studies have demonstrated that endothelial cells exposed to laminar shear stress are protected from apoptotic stimuli such as tumor necrosis factor (TNF)-alpha. The authors investigated the role of phosphatidylserine (PS) in this phenomenon. Western blot analysis of cleaved caspase
Katarzyna Gajos et al.
Analytical and bioanalytical chemistry, 409(4), 1109-1119 (2016-11-09)
Among the various biomarkers that are used to diagnose or monitor disease, extracellular vesicles (EVs) represent one of the most promising targets in the development of new therapeutic strategies and the application of new diagnostic methods. The detection of circulating
Anne Jäkel et al.
Protein & cell, 1(2), 188-197 (2011-01-05)
The role of surfactant protein A (SP-A) in the recognition and clearance of apoptotic cells is well established, but to date, it is still not clear which surface molecules of apoptotic cells are involved in the process. Here we present
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Numéro d'article de commerce international

RéférenceGTIN
840039P-10MG04061835228768
840039P-200MG04061835228775