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791639C

Avanti

15:0-18:1-d7-PS

Avanti Research - A Croda Brand

Synonyme(s) :

1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phospho-L-serine (sodium salt)

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A propos de cet article

Formule empirique (notation de Hill) :
C39H66 D7 NNaO10 P
Numéro CAS:
Poids moléculaire :
777.00
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
Assay:
>99% (TLC)
Form:
liquid
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assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (791639C-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

1 mg/mL (791639C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phospho-L-serine (sodium salt) is a is a deuterated phospholipid. The lipid comprises phosphatidylserine attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phosphatidylserine is a component of inner cell membrane and is present in metabolically active sites. It is enriched in myelin sheath and is an acidic phospholipid.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH LIPIDOMIX Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Application

15:0-18:1-d7-PS (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phospho-L-serine (sodium salt)) has been used:
  • as a component of extraction solvent for lipid isolation from biological samples
  • as an internal standard to spike cell lysate and to quantify lipid species using fourier transform mass spectrometry (FTMS) analysis
  • as an internal standard to spike liver homogenate to quantify lipids by shotgun-electrospray ionization tandem mass spectrometry (ESI-MS)

Biochem/physiol Actions

Phosphatidylserine (PS) coordinates many regulatory functions and is a modulator of enzymes, channels and various receptors. PS supplementation provides relief from exercise induced stress. PS is essential for neurotransmission, prevents nerve cell deterioration and supports cognitive functionality.

Packaging

2 mL Amber Glass Sealed Ampule (791639C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC


pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash



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Tong Liu et al.
Expert review of proteomics, 17(3), 233-242 (2020-04-21)
Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is critical for decreasing the mortality.Method: A conjunctive lipidomic approach was employed to investigate the differences in
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using



Numéro d'article de commerce international

RéférenceGTIN
791639C-1MG04061837665882