14365C
EX-CELL® CD CHO Fusion
Animal-component free, without L-glutamine, without hypoxanthine, without thymidine, liquid, sterile-filtered, suitable for cell culture
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About This Item
NACRES:
NA.75
UNSPSC Code:
12352207
Quality Level
sterility
sterile-filtered
product line
EX-CELL®
form
liquid
technique(s)
cell culture | mammalian: suitable (suspension)
components
L-glutamine: no
shipped in
ambient
storage temp.
2-8°C
General description
EX-CELL® CD CHO Fusion is a chemically defined, animal-component free medium developed for the long-term growth of Chinese Hamster Ovary (CHO) cells. The absence of any large macro molecules allows for isolation and purification of secreted proteins from the cells. This medium is supplied without L-glutamine to aid in media stability, to avoid L-glutamine degradation that causes ammonia build-up and to provide an appropriate medium for the culture of CHO cells using glutamine synthetase selection (example: MilliporeSigma’s CHOZN GS knockout cell line). This medium does not contain hypoxanthine or thymidine to allow for its use with dihydrofolate reductase(DHFR-) gene amplification systems (example: MilliporeSigma’s CHOZN DHFR knockout cell line).
Preparation Note
Formulated to contain 20.9 grams of powder per liter of medium.
Legal Information
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Donot freeze. Protect from light. Several components of the medium arelight labile and should not be exposed to light for lengthy periods of time.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
How the Cellicon® filter and controller enables seamless adoption of a perfused N-1 seed train step into the cell expansion process.
Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion
Cellvento 4CHO-X Expansion Medium enhances cell biomass for bioreactor inoculation in cell expansion stages.
Qiong Wang et al.
Biotechnology and bioengineering, 116(9), 2303-2315 (2019-05-08)
With the increasing demand to provide more detailed quality attributes, more sophisticated glycan analysis tools are highly desirable for biopharmaceutical manufacturing. Here, we performed an intact glycopeptide analysis method to simultaneously analyze the site-specific N- and O-glycan profiles of the
Noriko Yamano-Adachi et al.
Scientific reports, 10(1), 17612-17612 (2020-10-21)
Chinese hamster (Cricetulus griseus) ovary-derived Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for the industrial production of recombinant therapeutics because of their ability to fold, assemble, and perform post-translational modifications, such as glycosylation, on proteins.
Weiyi Liu et al.
Biotechnology progress, 37(1), e3061-e3061 (2020-08-05)
Antibody-dependent cellular cytotoxicity (ADCC) is the primary mechanism of actions for several marketed therapeutic antibodies (mAbs) and for many more in clinical trials. The ADCC efficacy is highly dependent on the ability of therapeutic mAbs to recruit effector cells such
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 14365C-100BD | 04061838437327 |
| 14365C-10B | 04061838437334 |
| 14365C-10X1B | 04061838437341 |
| 14365C-200BD | 04061837504532 |
| 14365C-200BFS | 04061837504549 |
| 14365C-20B | 04061838437358 |
| 14365C-1000ML | 04061838821966 |
| 14365C-100BFS | 04061838438263 |
| 14365C-2X5B | 04061838437365 |
| 14365C-500ML | 04061838437372 |
| 14365C-50B | 04061838437389 |